What is the name of the reaction, which a virologist must apply for the detection of specific antigens in the rapid diagnosis of herpes simplex virus type I?
IFT with monoclonal antibodies # RIA AT HAIT NT Hemadsorption inhibition test
19. What specific structures can virologist finds in patients with herpes simplex type I? Tsank cells. Intranuclear inclusion cowdry # Cells' node-Negri Guarneri cells. Paschen cells. Lipschutz cells
1. What is the taxonomic position of causative agents of genital herpes (HSV-2)? Family Herpesviridae, subfamily Alphaherpesvirinae, genus Simplex herpes virus type II # Family Herpesviridae, subfamily Alphaherpesvirinae, genus Morbilivirus Family Hepadnaviridae, subfamily Alphaherpesvirinae, Simplex herpes virus type I Family Paramyxoviridae, genus Rubulavirus Family Paramyxoviridae, genus Respiroviru s
2. What is form of the oral genital virus? Spherical shape #Bullet form Brick-form Filiform
3. Describe the genome structure of genital herpes virus Double- stranded, linear DNA, in the form of the capsid, the virus has a long (L) chain and short (S) chain
# Single- stranded fragmented positive-sense RNA Double- stranded fragmented negative-sense RNA Single- stranded non fragmented negative-sense -RNA Single- stranded fragmented negative-sense -DNA
4. Please give morphological characteristics of the nucleocapsid of the genital herpes virus Has icosahedra type symmetry Has envelop # It has helical symmetry type Has not envelop He has mixed symmetry type
5. Where does the oral herpes virus reproduce in the cell? In the nucleus # In the cytoplasm It starts in the nucleus and ends in the cytoplasm It starts in the cytoplasm and ends in the nucleus
6. Indicate the antigenic structure of the causative agent of genital herpes? gG1-gG2 #nucleoprotein (NP) M- antigen F-antigen G-antigen
7. How is the genital herpes transmitted? Genital mucous Baby may be infected during childbirth (perinatal infection).
# Upper respiratory tract Mucous membranes of the gastrointestinal tract Damaged skin
8. Are there virusemia with genital herpes? Yes #No
9. Give the characteristic of the immunity, which is formed at genital herpes? Local cellular and by delayed type general type-specific No autoimmunity # Local non-specific short cellular General group-specific humoral Local and general humoral non-protective Type-specific non-protective There is autoimmunity
10. What complications may arise in the disease of genital herpes? Baby infection during pregnancy
Infertility
# Carcinoma of the genital tract
Encefalitis
Pneumonitis and coagulopaty in newborn
Renal impairment Violation of liver function No Complications
11. What material are taken for laboratory research at the genital herpes infection? Blood
Material from vesicle
Sperm
# Nasal-pharyngeal secretion Autopsy material Urine Feces Liquor Arthropods
12. Where does accumulate the causative agent of genital herpes in virological research? Chicken embryos Cell culture of human embryo In the body of laboratory animals # none of the above is available
13. How is indication of the causative agent of genital herpes in virological research made? Presence of clinical signs of infection or death of experimental animals CPE
Formation of the plaques on chicken embryos #HAT and hem-adsorbing none of the above is available
14. How is identification of the causative agent of genital herpes in virological research made? Light microscopy of preparations for the detection of Cowdry’s inclusions
ELISA
IFT NT # HI CFT, None of the above
15. What are the serological diagnostic methods for oral herpes? CFT ELISA
# HI
IFT AT
16. What are the methods of laboratory diagnosis of herpes simplex virus type II? Microscopical examination Virological. Serological Method of rapid diagnosis # Bacteriological Skin-allergic tests PCR
17. What is the specific prophylaxis of genital herpes? Live vaccine
Groups at risk #Vaccination not carried out.
Vaccinating at the beginning of the epidemic season Live, killed, chemicals, vaccines subunits γ - globulins Vaccinating by the immunization calendar All population Serum
1. What is the taxonomic position of causative agents of varicella-zoster virus infection? Family Herpesviridae, subfamily A lphaherpesvirinae, genus Varicellovirus. # Family Herpesviridae, subfamily Alphaherpesvirinae, genus Morbilivirus Family Hepadnaviridae, subfamily Alphaherpesvirinae, Simplex herpes virus type I Family Paramyxoviridae, genus Rubulavirus Family Paramyxoviridae, genus Respirovirus
2. What is form of the varicella-zoster virus? Spherical shape # Bullet form brick-form Filiform
3. Describe the genome structure of varicella-zoster virus Linear double-stranded DNA: the virus has a long (L) chain and short (S) chain, in the form of the capsid # Single- stranded fragmented positive-sense RNA Double- stranded fragmented negative-sense RNA Single- stranded non fragmented negative-sense -RNA Single- stranded fragmented negative-sense -DNA
4. Please give morphological characteristics to the nucleocapsid of the varicella-zoster virus Has icosahedra type symmetry Has envelop # It has helical symmetry type Has not envelop He has mixed symmetry type
5. Where does the reproduction of varicella-zoster virus take place in the cell? In the nucleus # In the cytoplasm It starts in the nucleus and ends in the cytoplasm It starts in the cytoplasm and ends in the nucleus
6. Indicate the antigenic structure of the causative agent of varicella-zoster gG1-gG2 #nucleoprotein (NP) M- antigen F-antigen G-antigen
7. What are the ways of transmission of the causative agent varicella zoster? Contact - a separation of vesicles (contact with a person sick with chickenpox or zoster patients). Aerogenic. # If you had sex with a sick person. When blood. Parenteral. Transmissible. When bitten
8. Are there virusemia with varicella zoster virus infection? Yes #No
9. Give the characteristic to the immunity which formed at varicella zoster virus infection? Local cellular and by delayed type-specific No autoimmunity # Local non-specific short cellular general group-specific humoral Local and general humoral non-protective type-specific non-protective There is autoimmunity
10. What complications may arise after varicella zoster virus infection? Encephalitis
Baby infection during pregnancy
# Carcinoma of the genital tract
Infertility
Pneumonitis and coagulopaty in newborn
Renal impairment Violation of liver function No Complications
11. What material is taken for laboratory research at the varicella zoster virus infection? Blood
Material from vesicle
# Nasal-pharynx secretion
Sperm
Autopsy material Urine Feces Liquor Arthropods
12. Where is the accumulation of the varicella- zoster virus in virological research? Cell culture # In the body of laboratory animals Chicken embryos
none of the above is available
13. How is indication of the varicella- zoster virus in virological research made? CPE
# Presence of clinical signs of infection or death of experimental animals
Formation of the plaques on chicken embryos HAT and hem-adsorbing none of the above is available
14. How is identification of the causative agent of varicella zoster virus in virological research made? CFT Light microscopy of preparations for the detection of inclusions (calf Lipschutz) IFT. ELISA. NT. # Light microscopy of preparations for the detection of cowdry’s inclusions
HAIT. Hem-agglutination.
15. What are the serological diagnostic methods for varicella zoster virus infection? CFT ELISA
NT
# HI
IFT AT
16. What are the specific prophylaxis of varicella zoster virus infection? Live vaccine
Groups at risk γ - globulins
#Vaccination not carried out.
Vaccinating at the beginning of the epidemic season Live, killed, chemicals, vaccines subunits vaccinating by the immunization calendar All population Serum
1. What is the taxonomic position of causative agents of Cytomegalovirus infection? Family Herpesviridae, subfamily Betaherpesvirinae, genus Cytomegalovirus. # Family Herpesviridae, subfamily Alphaherpesvirinae, genus Morbilivirus Family Hepadnaviridae, subfamily Alphaherpesvirinae, Simplex herpes virus type I Family Paramyxoviridae, genus Rubulavirus Family Paramyxoviridae, genus Respirovirus
2. What is form of the Cytomegalovirus? Spherical shape # Bullet form Brick-form Filiform
3. Describe the genome structure of Cytomegalovirus. Linear double-stranded DNA: the virus has a long (L) chain and short (S) chain, in the form of the toroid # Single- stranded fragmented positive-sense RNA Double- stranded fragmented negative-sense RNA Single- stranded non fragmented negative-sense -RNA Single- stranded fragmented negative-sense -DNA
4. Please give morphological characteristics to the nucleocapsid of Cytomegalovirus. Has icosahedra type symmetry Has envelop # It has helical symmetry type Has not envelop He has mixed symmetry type
5. Where does the Cytomegalovirus reproduce in the cell? In the nucleus # In the cytoplasm It starts in the nucleus and ends in the cytoplasm It starts in the cytoplasm and ends in the nucleus
6. Indicate the antigenic structure of the causative agent of Cytomegalovirus infection gG1-gG2 #nucleoprotein (NP) M- antigen F-antigen G-antigen
7. What are the ways of transmission of the causative agent Cytomegalovirus infection? Contact: with the passage of the fetus during labor. The placenta When feeding the baby. When hemo-transfusion. When sexual contact with sick person
# Transmissible. When bites.
8. Are there virusemia with Cytomegalovirus infection? Yes #No
9. Give the characteristic to the immunity which is formed at Cytomegalovirus infection Humoral cellular type-specific No autoimmunity # Local non-specific short cellular general group-specific humoral Local and general humoral non-protective type-specific non-protective There is autoimmunity
10. What complications may arise after Cytomegalovirus infection? Encephalitis
Baby infection during pregnancy.
# Carcinoma of the genital tract
Infertility
Pneumonitis and coagulopaty in newborn
Renal impairment Violation of liver function No Complications
11. What materials are taken for laboratory research at the Cytomegalovirus infection? Blood
Urine Liquor Saliva
Material from uterine
Biopsy from kidneys
# Nasal-pharynx secretion
Sperm
Autopsy material Feces Arthropods
12. Where is the accumulation of the Cytomegalovirus in virological research? Cell culture # In the body of laboratory animals Chicken embryos
none of the above is available
13. How is indication of the Cytomegalovirus in virological research made? CPE
Presence of the intra-nuclear inclusions
#Presence of clinical signs of infection or death of experimental animals
Formation of the plaques on chicken embryos HAT and hem-adsorbing none of the above is available
14. How is identification of the causative agent of Cytomegalovirus in virological research made? IFT. ELISA. # CFT Light microscopy of preparations for the detection of inclusions (calf Lipschutz). Light microscopy of preparations for the detection of Cowdry’s inclusions
HAIT. NT. Hem-agglutination.
15. What are the serological diagnostic methods for Cytomegalovirus infection? CFT ELISA
NT
# HI
IFT AT 16. What is the specific prophylaxis of Cytomegalovirus infection? Live vaccine
Groups at risk # γ - globulins
Vaccination not carried out.
Vaccinating at the beginning of the epidemic season Live, killed, chemicals, vaccines subunits Vaccinating by the immunization calendar All population Serum
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