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What are the diseases caused by Epstein-Barr virus?

Infectious mononu­cleosis

Nasopharyngeal carcinoma,

Lymphomas,

Burkitt's lymphoma

#HIV infection

Cytomegalovirus infection

7. What are the ways of transmission of the Epstein-Barr virus?
When hemo-transfusion.
Aerogenic.
# When sexual contact with sick person

Transmissible.
The placenta.
When feeding the baby

Contact: with the passage of the fetus during labor.
When bites.

8. Are there virusemia with Epstein-Barr virus infection?
Yes
#No

9. Give the characteristic to the immunity, which formed at Epstein-Barr virus infection?
Humoral type specific long life

No autoimmunity
# Local non-specific short cellular
general group-specific cellular

Local and general humoral non-protective
type-specific non-protective
There is autoimmunity

10. What complications may arise after Epstein-Barr virus infection?
Anemia

Encephalitis

Hepatitis

Pneumonia

# Baby infection during pregnancy

Carcinoma of the genital tract

Infertility

Pneumonitis and coagulopaty in newborn

Renal impairment
Violation of liver function
No Complications

11. What material are taken for laboratory research at the Epstein-Barr virus infection?
Blood

lymphoid tissue

Saliva

# Material from uterine

Biopsy from kidneys

Urine
Liquor
Nasal-pharynx secretion

Sperm

Autopsy material
Feces
Arthropods

12. Where is the accumulation of the Epstein-Barr virus in virological research?
Cell culture
# In the body of laboratory animals
Chicken embryos

none of the above is available

13. How is indication of the Epstein-Barr virus in virological research made?
CPE

Presence of the intra-nuclear inclusions

# Presence of clinical signs of infection or death of experimental animals

Formation of the plaques on chicken embryos
HAT and hem-adsorbing
none of the above is available

14. How is identification of the causative agent of Epstein-Barr virus in virological research made?
IFT.
ELISA.
# CFT
Light microscopy of preparations for the detection of inclusions (calf Lipshyuttsa). Light microscopy of preparations for the detection of Koudri’s inclusions

HAIT.
NT.
Hemagglutination.

15. What are serological diagnostic methods for Epstein-Barr virus infection?
IFT
ELISA

# NT

HI

IFT
AT

16. What is the specific prophylaxis of Epstein-Barr virus infection?
Specific prophylaxis not carried out.

#Live vaccine

Groups at risk
γ - globulins

Vaccinating at the beginning of the epidemic season
Live, killed, chemicals, vaccines subunits
Vaccinating by the immunization calendar
All population
Serum

1. Vesicles appeared in patients with herpes infection of the skin, mucous membranes. What test for rapid diagnosis is used by virologist for the detection of herpes simplex virus in material from vesicles?
+ IFT.
NT.
CFT.
HAIT.
Precipitation test.

2. For the diagnosis of generalized herpetic infection virologist investigated serum to detect specific antibodies. Which class of antibodies showed acute stage of viral infection?
+Ig M.
Ig A.
Ig E.
Ig G.
Ig D.

3. In mother and child were detected specific IgG against cytomegalovirus infection. How can you explain the results?
+ Transplacental transfer of antibodies.
Transplacental infection of the fetus.
The immune response of infected fruit.
Infection of a newborn during childbirth.
EM-defect in the immune system of a newborn.

4. Doctor found in the student of African a Burkett’s lymphoma. What is the causative agent of the disease?
+ Epstein-Barr virus.
The herpes-zoster virus.
Herpes simplex virus serotype 1.
Herpes simplex virus serotype 2.
Cytomegalovirus.

5. What are the causative agents of the infectious diseases that can cause an acquired immunodeficiency and directly reproduce in cells of the immune system and destroys them?
+ Kissing disease, AIDS.
TB mycobacteriosis.
Polio, hepatitis A.
dysentery, cholera.
Q-fever, typhus.

6. In patients who received therapy immunodepresant about systemic diseases manifest signs of activation of CMV infection. What is the diagnostic method to be used to confirm the diagnosis?
+ Detection of specific IgM using ELISA.
Infection of white mice
Study of paired sera
Study of cellular immunity
Detection of antibody by pH

7. The physician suspected angina in the student who was admitted to the infectious hospital. What are the results of laboratory studies which confirm the diagnosis in a patient after his hospitalization?
+ Detection of Ig M - antibodies Epstein-Barr virus.
Detection of antibodies to cytomegalovirus.
Selection herpes virus.
Identification of a fourfold increase in titer of antibodies to Epstein-Barr virus.
Detection of Ig M - antibodies to herpes simplex virus.

8. Painful vesicles appeared in patient on the skin along the right facial nerve, causing itching. Application of antibiotic ointment was ineffective. Cause of this disease can be?
+ Herpes virus
Adenovirus.
Streptococcus.
Staphylococcus.
Bacillus.

11. The patient has made a complain about the appearance of painful vesicles on intercostal spaces. As a child patient had varicella zoster infaction. What is the diagnosis the doctor put the patient?
+ Herpes zoster
herpes simplex
allergic dermatitis
Erysipelas
hives.

12. Patients with infectious mononucleosis for continuous two weeks received glucocorticoids. Accumulate a remission, but also took exacerbation of chronic tonsillitis. The result of which is a complication?
+ Immunosuppressant.
antitoxic.
anti-allergic.
anti-inflammatory.

13. In the neurological department entered old woman complaining of a rash shingles character. The skin rash is a painful body, looks like bubbles with serous content. Which virus caused the disease?
+ Alpha-herpesvirus.
Beta-herpesvirus.
Gamma-herpesvirus.
HIV.
Poxvirus.

14. Child entered the hospital with high fever, enlarged lymph nodes, and rash. The doctor suspected infectious mononucleosis. Which virus caused the disease?
+ Epstein-Barr virus.
Cytomegalovirus.
Varicella - zoster virus.
Poxvirus.
HIV.

15. The doctor diagnosed the acute herpes in the patient's with increased body temperature, flushing and swelling of mucous membrane of cheeks with a small painful rash. Which drug do you recommend to appoint to the patient for treatment?
+ Acyclovir.
Herpetic immunoglobulin.
Immunoglobulin.
Ribavirin.
Live vaccine.

16. The doctor noted in patient continuous increase in body temperature, increased lymph nodes in the blood - a significant increase in lymphocytes. Epstein-Barr virus was detected by using ELISA. What is the diagnosis you put a patient?
+ Infectious mononucleosis
Lymphoma burkitt
Herpetic adenopathy
Generalized infection that is caused by a herpes-zoster.
Cytomegalovirus infection.

17. After kidney transplantation patient received the treatment to prevent organ rejection, but the signs of a generalized CMV infection appeared in him. What are the causes of this disease?
+Application of immunosuppressive therapy.
The reaction of graft against the host organism.
Manifestation histocompactabilty reaction.
Polyclonal B-lymphocyte stimulation
Depression viral genome.

18. Rash as hoop with a pain syndrome appeared in patients in the course intercostal nerves. What research is the most effective for rapid diagnosis of herpes zoster?
+ IFT with monoclonal antibodies
Accumulation of virus in cell culture.
NT.
ELISA.
CFT

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