Table 2. Sensitivity analysis assessing the impact of the 2013 ESH/ESC Guidelines on costs, proportion of benefits and efficiency.
doi:10.1371/journal.pone.0140793.t002
Fig 3. Age-related proportions of individuals to treat according to the PB strategy and the 2007 ESH/ESC guidelines.
Pie areas indicate the relative contributions of age classes to the overall number of subjects eligible to treatment referred to the ineligible individuals of all ages.
doi:10.1371/journal.pone.0140793.g003
Fig 4 shows the life-years gained as well as the years of potential life lost among the individuals potentially eligible under the ESH/ESC guidelines and the PB strategy. While the ESH/ESC guidelines allocate most of gains to the oldest men (relative life-year gain = 14%) with no benefit for women less than 45 years, health gains are proportional to the potential losses in all categories under the PB strategy (relative life-year gain = 10%); this implied increased numbers of life-years to preserve and thus greater NEPdes at younger ages with slightly decreased numbers in men and women over 55 years of age. The PB strategy yielded virtually the same number of life-years gained, as did the European rule.
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