Желудочно-кишечные
Инфаркт или резекция кишки (ниже двенадцатиперстной кишки), селезёнки, печени или жёлчного пузыря, когда-либо, по любым причинам (счёт 2, если более, чем в одном месте) Мезентериальная недостаточность Хронический перитонит
Стриктуры или хирургические операции на верхней части ЖКТ, когда-либо
Мышечно-скелетные Мышечная атрофия или слабость
Деформирующий или арозивный артрит (включая вправимые деформации, исключая аваскулярные некрозы) Остеопороз с переломами или коллапсом позвонков (исключая аваскулярный некроз) Аваскуляриый некроз (счёт 2, если >1) Остеомиелит
Кожные
Рубцующаяся хроническая алопеция Обширное рубцевание или панникулит (кроме скальпа и подушечек пальцев)
1(2)
1(2)
1(2)
1(2)
160 ♦ Ревматология ♦ Системная красная волчанка
Окончание табл. 3
|
| Изъязвление кожи (исключая тромбоз) в течение более 6 мес Преждевременная недостаточность гонад Сахарныйдиабет (вне зависимости от терапии) Малигнизация(исключая дисплазию) (счёт 2, если более одной локализации)
| 1 1 1 1(2)
| ЛИТЕРАТУРА
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СИСТЕМНАЯ СКЛЕРОДЕРМИЯ
Системная склеродермия — аутоиммунное заболевание соединительной ткани, основные клинические признаки которого обусловлены распространёнными нарушениями микроциркуляции, фиброзом кожи и внутренних органов. Системная склеродермия — важнейший представитель склеродермической группы болезней, к которым также относятся ограниченная (очаговая)склеродермия, диффузный эозинофильный фасци-ит, склередема Бушке, мультифокаль-ный фиброз, индуцированные формы склеродермии и псевдосклеродермичес-кие синдромы.
МКБ-10: М34 Системный склероз; М34.0 Прогрессирующий системный склероз; М34.1 Синдром CREST; M34.2 Системный склероз, вызванный лекарственными средствами и химическими соединениями; М34. 8 Другие формы системного склероза.
Аббревиатуры: ССД — системная склеродермия; ИЗЛ — интерстициальное заболевание лёгких.
ЭПИДЕМИОЛОГИЯ11
• Распространённость ССД различает ся между отдельными географически ми зонами и этническими группами, в том числе проживающими в одном ре гионе.
• Первичная заболеваемость колеблет ся от 3,7 до 19,0 на 1 млн населения в год.
• ССД чаще встречается у женщин (со отношение 5—7 к 1) в возрасте 30— 60 лет.
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