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Рак поджелудочной железыПрогноз при раке экзокринного отдела поджелудочной железы крайне неблагоприятный. Рак поджелудочной железы может быть чувствительным не только к факторам роста, но и к половым гормонам. В 1984 г. в опытах на животных мы установили, что трипторелин и соматостатин тормозят рост рака поджелудочной железы. Основываясь на этих результатах, мы применили трипторелин для лечения больных с неоперабельным раком поджелудочной железы 3-й и 4-й стадий. У некоторых больных отмечалось объективное улучшение, регрессия опухоли; повысилась выживаемость. Однако трипторелин нельзя считать препаратом выбора для лечения рака поджелудочной железы. Предварительные клинические испытания аналога соматостатина RC-160 показали, что этот препарат вызывает объективное улучшение у больных с раком поджелудочной железы III и IV стадий, позволяет значительно снизить дозы анальгетиков, а в отдельных случаях приводит к регрессии опухоли и к увеличению продолжительности жизни больных. 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The use of an LH-RH agonist (ICI 118630, Zoladex) in advanced premenopausal breast cancer. Br J Cancer 53:629, 1986. Приложения Приложение А. Исследование функции эндокринных желез с помощью стимуляционных и супрессивных проб Н. Штерн, Д. Гриффин Дата добавления: 2015-02-05 | Просмотры: 853 | Нарушение авторских прав |