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Introduction

Molecular biology studies the structure and function of nucleic acids, principles and mechanisms of genetics information, as well as the molecular basis of the structure and functions of the cage during the growth, development, division, tumor transformation and cell death.

Medical Genetics examines the reasons for the emergence and development of hereditary diseases, their diagnosis, prevention and treatment.

With an integrated approach to teaching in medical schools, the study of molecular biology provides basis for studying the molecular basis of structure and functioning of cells, regulating genes expression is necessary for understanding normal life processes and their disorders, leading to emergence of many diseases, including hereditary, associated with mutations in genes and chromosomes, which is the subject of medical genetics.

This fundamental training will allow to form clinical mentality, starting with the first-year students. student, studying molecular biology and medical genetics, learns about mechanisms of disorders the molecular, genetics and cellular bases of life processes and their role in the formation and manifestation of pathological conditions. And also their diagnosis and prevention basis.

This soda is theoretical basis for studying biological chemistry, histology, physiology, pathological physiology, general immunology, pharmacology, pediatrics, neurology, obstetrics gynecology, and other clinical discipline.

2.2. The purpose of discipline:

formation in students current knowledge about the basic molecular genetics and cellular mechanisms of functioning of the body and their application in clinical practice.

2.3. Learning objectives:

-understanding role of molecular genetics and cellular mechanisms of the body in health and disease for effective diagnosis, prevention and treatment of common diseases.

- To form an idea of ​​ basic principles of using modern molecular genetics techniques and technology in theoretical and practical medicine;

- learn to recognize the main features of hereditary pathologies for their timely diagnosis and prevention.

- to give an idea about ethical and legal standards usage of molecular genetics studies achievements in medicine;

-Learn skills from the scientific literature and electronic databases for hereditary diseases.

2.4. Learning outcomes:

The student must:

generate knowledge and ideas:

- about molecular genetics basis and cellular mechanisms of functioning of body, structural and functional organization of hereditary material at molecular level (DNA).

- About direction and mechanisms of genetics information transmission in living systems, their role and importance in functioning of living organisms in normal and pathological conditions.

- About the molecular mechanisms realization of genetics information.

-On structural and functional organization of hereditary material in gene, chromosomal and genomic level;

-About reasons and mechanisms of genetics variation and their role in formation of human hereditary diseases and congenital malformations;

- About the nature of heredity, inheritance types of traits (diseases), controlled by genes, and their usagt in medical practice for recognition hereditary nature of disease.

- about basic molecular genetics and cellular mechanisms of hereditary polymorphisms resulting from organism reactions to medications.

-On synthesis molecular basis and drugs use.

- About the molecular biological and genetics terms in international language.

- about legal aspects hereditary diseases preventing problems and congenital malformations.

To form ability:

· using knowledge of molecular and genetics processes to explain the mechanisms

development of disease;

· to define the main, and most common hereditary disease in human;

· differentiate between different types of chromosomes and recognize normal and abnormal human karyotypes;

· genealogical method used to determine the hereditary nature of disease;

· to use a special background material, molecular biological and genetics terms, electronic genetics databases, etc.

Be skilled:

· by Cognitive (knowledge), practical, communicative, legal and self-improvement.

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