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Lesson number 20

1.Title; Landmark control line. (Fundamentals of General Genetics)

2. Aims: To determine the level of understanding and assimilation of knowledge by students in general genetics and its role as the place of values ​​in modern medicine and health.

3. Assess the level of knowledge:

- understanding of individual sections of the students studied material.

-Identify the student's ability to recognize the types of inheritance of man.

4.Osnovnye topic questions:

4.1. Gennetika-the science of heredity and variation in the object task methods. Key terms and concepts of genetics. The value of genetics in medicine.

4.2. Mendel's laws.

4.3. Types of inheritance.

4.4.Mendeliruyuschie signs of man. Terms of Mendelian.

4.5. The concept of stsenlenii linkage group.

4.6. linked inheritance

4.7. Crossing-over mechanisms of evolutionary significance.

4.8. Mapping of genes important methods.

4.9. Chromosome theory of heredity basic provisions.

4.10. Genotype. Phenotype: the definition of relationship

4.11. Interaction alleles: recessively. Incomplete dominance. over dominance. Kodominirovanie.

4.12. Multiple alleles. Genetics of blood. The medical importance.

4.13. Vzaymodeystvie no allelic genes: complementarity. epistasis. polymers.

4.14. Penetrance. expressiveness. Pleyotoriya.

4.15. Photocopy. Genokopy.

4.16. Developmental Biology: a definition. types. periods.

4.17. The early stages of ontogeny: gametogenesis. fertilization. plyarnost. egg.

4.18. Cellular mechanisms of ontogeny.

4.19. Differential gene activity.

4.20. Homeotic genes. Homewood in humans and heritable disease.

4.21. Teratogens factors. Teratogens.

4.22.Kriticheskie periods of development.

4.23. Congenital malformations (birth defects): definition and cytogenetic mechanisms of their formation.

4.24. Classification. diagnosis and prevention of birth defects.

4.25. Population. definition. characteristics of the population.

4.27. Species populations and mating structure of populations.

4.28. Genetic characteristics of populations.

4.29. The elementary evolutionary processes. occurring in the populations and characteristics of their action in human populations.

4.30. Genetic load of populations. concept. medical importance.

4.31. Ecology. definition. Relationship of ecology and genetics.

4.32. environmentally caused disease in humans. mechanisms of their development.

4.33. Environmental contaminants. classification. effect.

4.34. Genetic effects of environmental contamination in areas of ecological trouble in Kazakhstan.

4.35. The value of pharmacokinetics in modern medicine and pharmacy.

4.36. Genetic control of the metabolism of drugs.
4.37. Hereditary diseases and conditions, triggered by medication.
4.38. Types of chromosomal sex determination
4.39. The role of the Y chromosome and autosomal genes in primary sex determination.
4.40. Secondary sex determination.
4.41. Dependent on the floor and the only restriction floor signs

4.42. Gynandromorphy, intersexes, hermaphroditic, and other sexual deviations, medical importance.
4.43. Cloning: Past, Present. the future.
4.44. Reproductive cloning.
4.45. Ethical and legal issues of cloning organisms.
4.46. Human Cloning: for and against.
4.47. Possible applications of cloning technology.
4.48. Cell therapy and therapeutic cloning.
4.49. The genetics of aging
4.50. The mechanism of aging

4.51. Tell a manifestation of the aging of molecular-cellular level
4.52. Modern theories of aging
4.53. The history of stem cell research
4.54. Achievements and prospects in the study of stem cells.
4.55. Stem cells in clinical practice
4.56. The synthesis of drugs with the use of gene technology.

4.57. Biotechnological synthesis of drug
4.58. The methodology of finding new drugs, biotechnology products, nennoy engineering in pathological conditions
4.59. The leading factors of ecological trouble in the area of the Semipalatinsk nuclear test site.
4.60. Leading factors ekologichkskogo trouble in the Aral Sea...

4.61. The results of the study of health in these regions.

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