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Theme: Polygenic (Multifactor) Human Diseases

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  1. Aims: To generate in students the knowledge of nonmendelian monogenic human disease.
  2. Diseases of the Central Nervous System
  3. Diseases of the Central Nervous System
  4. Diseases of the Central Nervous System
  5. Diseases of the Central Nervous System
  6. Diseases of the Central Nervous System
  7. Diseases of the Central Nervous System
  8. Diseases of the Central Nervous System
  9. Diseases of the Central Nervous System
  10. Diseases of the Central Nervous System

2. Object: form students’ modern knowledge of the causes, mechanisms of development, clinical manifestations, and medical-social significance of polygenic diseases.

 

3. Educational Tasks:

- reveal the essence of polygenic inheritance of signs;

- reveal the essence and the mechanisms of development of polygenic diseases;

- familiarize students with modern molecular-genetic mechanisms of development of polygenic diseases;

- reveal the essence of polygenicdiseases from the clinical point of view as diseases with congenital genetic predisposition;

- form students’ ability to analyze and recognize genetic predisposition to widely spread human diseases.

4. Principal Questions of the Theme:

4.1. Polygenic (multifactor) diseases, peculiarities of their manifestation, classification

4.2. Mechanisms of development of polygenic diseases

4.3. Associations of genetic markers with multifactor diseases

4.4. Main methods of research of polygenic diseases

5. Methods of Teaching: combined method of education (conversation, solution of situational problems)

6. Literature:

6.1. Bochkov N.P. Clinical Genetics. M., 2004, pp. 261-293

6.2. Genetics. Under redaction of Ivanov V.I. M., 2006, pp. 254-257

6.3. Ginter Y.K. Medical Genetics, M., 2003, pp. 222-239

6.4. Kuandykov Y.U. Fundamentals of General and Medical Genetics. A., 2008, pp. 44/54

6.5. Lilin Y.T. et al. Genetics for Physicians. M., 1990, pp. 66-67

6.6. Fogel F., Motulski A. Human Genetics. Volume 2. M., 1990, pp. 245-265

6.7. Chshipkov V.P., Krivosheina G.N. General and Medical Genetics. M., 2003, pp. 200-206

7. Control:

Дата добавления: 2015-09-18 | Просмотры: 529 | Нарушение авторских прав


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