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Handout material: test-2 version with 10 questions15. References: 15.1. Bochkov, NP, "Clinical Genetics" M Publishing House "GEOTAR-MED", 2005 pages 13,47-64,136-189,210-255,261-271. 15.2. Fuller, DM, Dennis Shilds.Molekulyarnaya cell biology. Guidelines for vrachey.M: Bean Press, 2006, pp. 110,123-125,169-171,186-187. 15.3. Inge-Vechtomov S.G.Genetika selektsii.M with the basics: High School 1989, pp. 23-54,85-108,496-498. 15.4. Biology" Mushkambarov N. "Molecular M: 2003. pp. 163,518-250. Page 139 from 221 15.5. "Genetics". Textbook for High Schools (edited by Academician of the RAMS Ivanov VI) 12-39,82-99,116-125,173-181 page. 15.6. Albert B. et al "Molecular Biology of the Cell." Translation from English Part 2 M: The world in 1994. 15.7. Introduction to Molecular Medicine ". Edited M.A.Paltseva.M: Medicine, 2004, pp. 11-32. 15.8. Ginter EK "Medical Genetics" M: 2003, pp. 22-27,64-141. 15.9. IF Zhimulev "General and Molecular Genetics", Novosibirsk, 2003, pp. 31-38,40-48,452. 15.10. F.Ayala, J. Kayger. "Modern genetics" M: World of 1988, Part 1, pp. 37-56,64-80, part 2, pp. 321,334-341, part 3, page 61
16. Control: 16.1.. Rating of cognitive competences (knowledge) 8.1.1. Quizzes on topics 8.1.2. Test Control-2 variant with 10 questions 8.2. Rating of competence skills 8.2.1. Fill the table: Table 1 Types of inheritance and clinical manifestations of monogenic nonmendelian diseases of person
16.2. Rating of competence, communication skills 16.3. 1. Work in small group role-playing game "pediatrician" (performed by the methodical recommendations developed for doing this task 16.4. The decision of situational problems. 3. In the medical-genetic consultation asked parents of a sick child to complain: for obesity, bulimia (overeating), small hands and feet, hypogonadism, mental retardation. In the study of DNA established that epigenetic mutation, methylation of cytosine bases of DNA in spermatogenesis, breach by appropriate expression genov.Postavte diagnosis of a sick child, identify the syndrome, the cause of the mechanism of disease. 4. In the medical-genetic consultation asked parents of a sick child to complaints: obesity, inappropriate laughter, galloping, to dance gait, mental retardation. In the study of DNA established that epigenetic mutation, methylation of cytosine bases of DNA in oogenesis, impaired expression of the genes. Place a diagnosis of a sick child, identify the syndrome, install the causal mechanism.
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