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Theme #11. Gene technologies in medicines production

2. The aim: to form at students ideas of contemporary methods of medicines development and production on the basis of genetically engineered technology application.

3. The tasks:

3.1. Synthesis of medicines with gene technologies application.

3.2. Biotechnological synthesis of medicines.

3.3. Methodology of search of new medicines, products of biotechnology, genetic engineering in pathological states.

4. Performance form: presentation compiling.

5. Performance criteria:

а) studying and selection of recent literary sources;

b) information processing and systematization;

c) plan designing;

d) bibliography compiling;

e) abstract and/or project work making up.

The structure of abstract work:

1) the title page (made up in due form);

2) the table of contents (consecutive statement with indication of the main sections page numbers);

3) introduction (substantiation of the researched problem, its importance and urgency; determination of the aims and tasks of work);

4) the main part (each section should reveal evidentially a particular problem or one of its aspects, be logic continuation of the previous material; tables, schemes, diagrams, figures can be presented in this section or they can be executed as annex to abstract work);

5) conclusion (the results are summed up, the deductions are formulated and recommendations are suggested);

6) the list of bibliography (made up in due form).

Requirements to presentation making up:

а) a presentation should be made on the basis of “Microsoft Power Point” program;

b) the number of slides should be no more than 10-15;

c) a presentation should be done skillfully, be available to perception, slides shouldn't be loaded by a text material;

d) the list of bibliography should be presented on the last slide.

6. Deadline: before the midterm control on the chapter “Fundamentals of general genetics”.

7. Criteria of assessment: - 100 points at maximum that corresponds to 100%

8. Bibliography:

8.1. Львова Л.В. Индивидуальный подход. – Провизор, №12, 2006.

8.2. Мендель Г. Опыты над растительными гибридами. // Труды Бюро по прикладной ботанике. 1910. Т. 3. №11. С. 479-529.

8.3. Пашутин С. Фармакогеномика и эра лекарственного милосердия. «Химия и жизнь» №2, 2005.

8.4. Global Technology Center, Health Research Institute. Personalized Medicine. The Emerging Pharmacogenomics Revolution. Pricewaterhouse Coopers, February, 2005.

8.5. International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome.Nature 431, P. 931-945

8.6. Vogel F. Modern problem der Humangenetik.Ergebnisse der InnerentMedizin und Kinderheilkunde, 1959, 12, 52-125.

8.7. - www.medicum/hnov/ru /docter/lib>ary/obsterics/Nisvander/24/php - cok

- www.rusmedserv.com/forum/printthread.php?t=1003-27k

- www.reterats.net/online/referat:php?d=rkr-a-3801-7k-

9. Check:

9.1. What methods of gene technology can be used in medicines production?

9.2. What medicines can be produced on the basis of gene technology?

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