Theme: Heredity. Types of inheritance. Independent monogenic inheritance of characteristics
2. Purpose:
- Create the students' knowledge about heredity, type of inheritance of monogenic inheritance independent of normal and pathologic features;
- To develop the motivation of the need to study the inheritance, types of inheritance,
independent inheritance of genes for understanding the genetic mechanisms of development
hereditary diseases;
- To develop communication skills in the analysis of heredity, the types of inheritance,
independent inheritance of monogenic diseases in humans;
- Develop practical competence by applying knowledge of the mechanisms of inheritance
Mendelian normal and pathological human traits in the process of typical and situational problems in genetics.
3. Learning objectives:
- Clarify the genetic nature of the terms: genotype, phenotype, and allelic
nonalleles genes monoalleles, dialleles and multiple alleles, homozygote,
heterozygote, gemizigote;
- To reveal the genetic mechanisms of Mendelian traits and conditions
Mendelian in healthy subjects and patients with hereditary diseases;
- Explain the need for knowledge of the types and mechanisms of inheritance of genes in normal
and hereditary diseases in medical practice.
4. Key questions the theme:
4.1. The object and purpose of genetics. Basic concepts and terminology of genetics: genotype, phenotype, allele (monoalleles, dialleles and multiple alleles), dominance, recessive, homozygote, heterozygote, gemizigote.
4.2. Laws of inheritance of man. Laws: uniformity of the first generation cleavage, independent of inheritance and their genetic basis.
4.3. Mendelian signs of man and the conditions necessary for their Mendelian.
The medical importance of knowledge mendelian signs of man.
5. Teaching methods: oral questioning aimed at clarifying the understanding of the nature of student goals and objectives of the training, skills, short, clear, logically presented and the ability to depict the digested material in the form of charts, graphs, drawings, testing and subsequent analysis of errors in the work group: an explanation and demonstration solving problems, filling schemes.
5.1.. Solving (Medical Biology and Genetics. Under. Ed. Kuandykova EW task on page 87-89, the task № 1-5,8-12).
5.2. Fill in the table "during gamete formation of independent inheritance."
The formation of gametes with independ inheritance
Types of inheritance
| Genotypes
| The resulting
gametes
| Monohybrid crossing
Polyhybrid crossing
| АА; Аа; Вв; сс
|
| Digihybrid crossing
| АаВв; ССдд
|
| Polyhybrid crossing
| ВВСсДд
|
|
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