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Theme: Cellular mechanisms of ontogenetic development

2. Purpose:

- Create the students' knowledge about the patterns and sequence of cellular changes in the course of normal ontogenetic development of man;

- To develop the motivation of the need to study the ontogeny of cellular mechanisms of ontogeny, which is the basis for the understanding of physicians abnormalities in the form of the CDF;

- To develop communication skills in the analysis of situational problems in violation of the cellular mechanisms of ontogenesis;

- Develop practical competence in the use of knowledge of normal ontogenetic development with assignments.

3.Learning objectives:

- To reveal the essence of ontogeny, ontogenesis types and periods;

- Explain the role and importance of gametogenesis and fertilization for normal ontogenetic development;

- To reveal the nature and significance of the polarity of the egg, ooplazmatic segregation, positional information, determination, differentiation, embryonic induction for the normal ontogenetic development;

- To disclose the nature and significance of cellular processes: reproduction (proliferation), migration, selective sorting, and apoptosis for the normal ontogenetic development;

- Explain the sequence and stages of fetal development of the human organism from a clinical point of view.

4. Key questions the theme:

4.1. Developmental Biology: definition, types, periods

4.2. The early stages of ontogeny: the polarity of the oocyte, segregation ooplazmatic, positional information, determination, differentiation, induction of embryonic

4.3. Cellular mechanisms of ontogenesis

a) the proliferation

b) migration

c) sorting

g) apoptosis

4.4. The role of disorders of cellular mechanisms of ontogeny in human pathology

5. Methods of study: oral questioning, aimed at clarifying the nature of student understanding of goals and objectives of the training, skills, short, clear, logically presented and the ability to depict the digested material in the form of charts, graphs, drawings, testing and subsequent analysis of errors in the work group: an explanation and demonstration of problem solving, completion of schemes.

6. Literature:

The main:

6.1. Zhimulev I.F. General and molecular genetics. Novosibirsk, 2006, page 369-389.

6.2. Medical biology and genetics. The manual for students under the editorship of prof. Kuandykov E.U. Almaty, 2004, page 208-227.

6.3. Kuandykov E.U. Bases of the general and medical genetics (course of lectures). Almaty, 2007, page 54-71.

6.4. Genetics. Under the editorship of Ivanov V. I.; M., 2006, page 291-314

The additional:

6.5. Alikhanyan S. I., Akifyev A.P., Chernin L.S. General genetics. M, 1985, page 344-368.

6.6. Biology. Under the editorship of Yarygin V. N. of Book 1. M, 2001, page 276-415.

6.7. To Inga-Vechtomov S.G. Genetics with selection bases. M, 1989, page 409-429.

6.8. Korochkin L.I. Introduction in development genetics. M, 1999, 252 pages.

6.9. Nurtazin S. T., Vsevolodov E.B. Biology of individual development. And., 2005, 260 pages.

6.10. Medical genetics: studies. grant / Robert L.Nyyussbaum, Roderich of R, Macque-Innes, Huntington F.Willard: the lane with English. A.Sh.Latypov; under the editorship of N. P. Bochkov. - M: GEOTAR-media, 2010, page 254-259, 355-379

7. Control:

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