ЗАКЛЮЧЕНИЕ. Исследование сложных респираторных физиологических процессов требует применения большого количества функциональных тестов
Исследование сложных респираторных физиологических процессов требует применения большого количества функциональных тестов. Нет какого-либо отдельного теста исследования респираторной функции, предоставляющего желаемую информацию по отдельному пациенту. В то же время не нужно использовать все имеющиеся тесты в программе исследования единичного пациента. Некоторые тесты очень просты и должны проводиться каждому пациенту с подозреваемой или установленной сердечно-легочной патологией (спирометрия), так же как выполняются исследования артериального давления, ЭКГ и др.
Легочные функциональные тесты позволяют оценить влияние заболевания на респираторную функцию, и не дают возможности поставить точный диагноз, тем не менее они являются важной и необходимой частью клинического обследования пациентов.
СПИСОК ЛИТЕРАТУРЫ
1.Hutchinson J: On the capacity of the lungs and on the respiratory functions, with a view of establishing a precise and easy method of detecting diseases by the spirometer. Trans Med Soc Lond 29:137-252, 1846.
2.Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for Diagnosis, Management, and Prevention of COPD. 2006.
3.Global Initiative for asthma. Global Strategy for Asthma Management and Prevention. 2006
4.Beckles M.A., Spiro S.G., Colice G.L., Rudd R.M. - Lung Cancer Guidelines. The Physiologic Evaluation of Patients With Lung Cancer Being Considered for Resectional Surgery. Chest. 2003. 123; 1 (suppl.): 105s-114s.
5.Eagle KA, Berger PB, Calkins H, Chaitman BR, Ewy GA, Fleischmann KE, Fleisher LA, Froehlich JB, Gusberg RJ, Leppo JA, Ryan T, Schlant RC, Winters WL Jr, Gibbons RJ, Antman EM, Alpert JS, Faxon DP, Fuster V, Gregoratos G, Jacobs AK, Hiratzka LF, Russell RO, Smith SC - American College of Cardiology/American Heart Association Task Force on Practice Guidelines. - ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery---executive summary a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2002 Mar 12;105(10):1257-67.
6.BTS guidelines. Guidelines on the selection of patients with lung cancer for surgery. Thorax. 2001. 56; 2: 89-108.
7.Cykert S., Kissling G., Hansen C.J. - Patient preferences regarding possible outcomes of lung resection. What outcomes should preoperative evaluations target? Chest. 2000. 117: 1551-1559.
8.Datta D., Lahiri B. - Preoperative evaluation of patients undergoing lung resection surgery. Chest. 2003. 123; 6: 2096-2103.
9.Marx J.J., Punjabi N., Schwartz A., Varon J., Marik P., Shulman M. S., Smetana G. W. - Preoperative Pulmonary Evaluation. N Engl J Med 1999. 341: 613-614.
10.Reilly J.J. - Evidence-based preoperative evaluation of candidates for thoracotomy. Chest. 1999. 116 (suppl.):474S-476S.
11.Reilly J.J. - Preparing for pulmonary resection: preoperative evaluation of patients. Chest. 1997. 112 (suppl.): 206S-208S.
12.Schuurmans M.M., Diacon A.H., Bolliger C.T. - Lung Cancer. Functional evaluation before lung resection. Clin. Chest Med. 2002. 23; 1: 159-172.
13.Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CPM, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J - Standardisation of spirometry. Series “ATS/ERS task force: standardisation of lung function testing”. Edited by V. Brusasco, R. Crapo and G. Viegi. Number 2 in this Series. Eur Respir J 2005; 26: 319 - 338.
14.American Thoracic Society. Standardization of spirometry: 1994 update. Am J Respir Crit Care Med 1995; 152: 1107-1136.
15.Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J. 1993, 6: suppl. 16, 5-40.
16.Swanney MP, Jensen RL, Crichton DA, Beckert LE, Cardno LA, Grapo RO. - FEV6 is an acceptable surrogate for FVC in the spirometric diagnosis of airway obstruction and restriction. Am J Respir Crit Care Med 2000; 162: 917-920.
17.Enright PL, Connett JE, Bailey WC. - FEV1/FEV6 predicts lung function decline in adult smokers. Respir Med 2002; 96: 444-449.
18.Cosio M, Ghezzo H, Hogg JC, et al: The relations between structural changes in small airways and pulmonary-function tests. N Engl J Med 1978, 298: 1277-1281.
19.Cochrane GM, Prieto F, Clark TJ: Intrasubject variability of maximal expiratory flow volume curve. Thorax 1977, 32: 171-176.
20.McDonald J.B., Cole T.J. The flow-volume loop: reproducibility of air and helium-based tests in normal subjects. Thorax 1980, 35: 64-69.
21.Гриппи МА. - Патофизиология легких. М. «Издательство Бином»; СПб. «Невский диалект». 1999.
22.Wright BM, McKerrow CB: Maximum forced expiratory flow rate as a measure of ventilatory capacity: With a description of a new portable instrument for measuring it. BMJ 1959, 5159: 1041-1046.
23.Hyatt RE, Scanlon PD, Nakamura M. - Interpretation of pulmonary function test: a practical guide. Lippincott Williams and Wilkins. 2003.
24.Berend N, Thurlbeck WM: Correlations of maximum expiratory flow with small airway dimensions and pathology. J Appl Physiol 1982, 52: 346-351.
25.Knudson RJ, Lebowitz MD, Holberg CJ, et al: Changes in the normal maximal expiratory flow-volume curve with growth and aging. Am Rev Respir Dis 1983, 127: 725-734.
26.Despas PJ, Leroux M, Macklem PT: Site of airway obstruction in asthma as determined by measuring maximal expiratory flow breathing air and a helium-oxygen mixture. J Clin Invest 1972, 51: 3235-3243.
27.Hyatt RE. The interrelationship of pressure, flow and volume during various respiratory maneuvers in normal and emphysematous patients. Am. Rev. Respir. Dis. 1961; 83: 676 - 683.
28.Ferris BG: Epidemiology: Standardization project. Am Rev Respir Dis 1978, 118: 1-120.
29.Rochester DF, Arora NS, Braun NMT, et al: The respiratory muscles in chronic obstructive pulmonary disease (COPD). Bull Eur Physiopathol Respir 1979, 15: 951-975.
30.Pierce RJ, Brown DJ, Holmes M, Cumming.G, Denison DM - Estimation of lung volumes from chest radiographs using shape information. Thorax. 1979, 34: 726-734.
31.Ross JC, Copher DE, Teays JD, Lord TY Functional residual capacity in patients with pulmonary emphysema. Ann. Intern. Med. 1962, 57: 18-28.
32.Tierney DF, Nadel JA - Concurrent measurements of functional residual capacity by three methods. J Appl Physiol. 1962, 17: 871-873.
33.Pare PD, Wiggs BJ, Coppin CA. - Errors in the measurement of total lung capacity in chronic obstructive lung disease. Thorax. 1983, 38: 468-471.
34.Darling RC, Cournand A, Richards DWJ - Studies on intrapulmonary mixture of gases. III. Open circuit methods for measuring residual air. J Clin Invest. 1940, 19: 609-618.
35.Fleming GM, Chester EH, Saniie J, et al - Ventilation inhomogeneity using multibreath nitrogen washout: Comparison of moment ratios and other indexes. Am Rev Respir Dis 1980, 121: 789-794.
36.Brunner JX, Wolff G, Gumming G, Langenstein H. - Accurate measurement of N2 volumes during N2 washout requires dynamic adjustment of delay time. J Appl Physiol. 1985, 59: 1008-1012.
37.Tammeling GJ, Quanjer PhH - Contours of Breathing 1. Ingelheim am Rhein: CH Boehringer Sohn, 1979.
38.Hathiral S, Renzetti ADJr, Mitchell M. - Measurement of the total lung capacity by helium dilution in a constant volume system. Am Rev Respir Dis. 1970, 102: 760-770.
39.Martin R, Macklem PT: Suggested Standardized Procedures for Closed Volume Determinations (Nitrogen Method). Bethesda: Division of Lung Disease, National Heart and Lung Institute, NIH, 1973.
40.Mitchell MM, Renzetti AD Jr: Evaluation of a single-breath method of measuring total lung capacity. Am Rev Respir Dis 1968, 97: 571-580.
41.Cotes JE. - Transfer factor (diffusing capacity). Bull Eur Physiopathol Respir. 1983, 19: suppl. 5, 39-44.
42.Quanjer PkH, de Pater L, Tammeling GJ. - Plethysmographic Evaluation of Airway Obstruction. Leusden: Netherlands Asthma Foundation, 1971.
43.DuBois AB, Botelho SR, Bedell GN, Marshall R, Comroe JHJr. - A rapid plethysmographic method for measuring thoracic gas volume; a comparison with a nitrogen wash-out method for measuring functional residual capacity. J Clin Invest. 1956, 35: 322-326.
44.Mead J. Volume displacement body plethysmograph for measurements on human subjects. J Appl Physiol. I960, 15: 736-740.
45.Nolle D, Reif E, Ulmer WT. - Die Ganzkorperplethysmographie. Methodische Probleme und Praxis der Bestimmung des intrathorakalen Gasvolumens und der Resistance-Messung bie Spontanatmung. Respiration. 1968, 25: 14-34.
46.Rodenstein DO, Francis C, Stanescu DC. - Airway closure in humans does not result in overestimation of plethysmographic lung volume. J Appl Physiol. 1983, 55: 1784-1789.
47.Van de Woestijne KP, Bouhuys A. - Spirometer response and pressure correction in body plethysmography. Prog Respir Res. 1969, 4: 64-74.
48.Bryant GH, Hansen JE. - An improvement in whole body plethysmography. Am Rev Respir Dis. 1975, 112: 464-465.
49.Stanescu DC, Rodenstein P, Cauberghs M, et al: - Failure of body plethysmography in bronchial asthma. J Appl Physiol. 1982, 52: 939-948.
50.Rodenstein DO, Stanescu DC. - Reassessment of lung volume measurement by helium dilution and body plethysmography in chronic airflow obstruction. Ibid. 1982, 126: 1040-1044.
51.Shore S, Milic-Emili I, Martin JG. - Reassessment of body plethysmographic technique for the measurement of thoracic gas volume in asthmatics. Ibid. 1982, 126: 515-520.
52.Habib MP, Engel LA. - Influence of panting technique on the plethysmographic measurement of thoracic gas volume. Am Rev Respir Dis. 1978, 117: 265-271.
53.Bush A, Denison DM - Use of different magnification factors to calculate radiological lung volumes. Thorax. 1986, 41: 158-159.
54.Pierce RJ, Brown DJ, Denison DM. - Radiographic, scintigraphic and gas dilution estimates of individual lung and blood volumes in man. Thorax. 1980, 35: 777-780.
55.Barnhard HJ, Pierce JA, Joyce JW, Bates JH. - Roentgenographic determination of total lung capacity. Am J Med. 1960, 28: 51-60.
56.Loyd HM, String TI, DuBois AB. - Radiographie and plethysmographic determination of total lung capacity. Radiology. 1966, 86: 7-14.
57.Reger RB, Young A, Morgan WKC. - An accurate and rapid radiographie method for determining total lung capacity. Thorax. 1972, 27: 163-168.
58.Pratt PC, Klugh GH. - A method for the determination of total lung capacity from postero-anterior and lateral chest roentgenograms. Am Rev Respir Dis. 1967, 96: 548-552.
59.Rodenstein DO, Sopwith TA, Stanescu DC, Denison DM. - Re-evaluation of the radiographic method for measurement of total lung capacity. Bull Eur Physiopathol Respir. 1985, 21: 521-525.
60.Harris TR, Pratt PC, Kilburn KH. - Total lung capacity measured by roentgenograms. Am J Med. 1971, 50: 756-763.
61.Gelb AF, Gold WM, Wright RR, et al. - Physiologic diagnosis of subclinical emphysema. Am Rev Respir Dis. 1973, 107: 50-63.
62.Gelb AF, Gold WM, Nadel JA. - Mechanisms limiting airflow in bullous lung disease. Am Rev Respir Dis. 1973, 107: 571-578.
63.Vogel J., Smidt U. - Impulse oscillometry: analysis of lung mechanics in general practice and the clinic, epidemiological and experimental research. - Frunkfurt am Main; Sennwald; Wein: pmi - Vrl.Gruppe, 1994.
64.Du Bois AB, Brody W, Lewis DH, Burgess BF. - Oscillation mechanics of lung and chest in man. J Appl Physiol. 1956, 8: 587-594.
65.Landser FJ, Nagles J, Demedts M, et al. - A new method to determine frequency characteristics of the respiratory system. J Appl Physiol. 1976, 41: 101-106.
66.Michaelson ED, Grassman ED, Peters WR. - Pulmonary mechanics by spectral analysis of forced random noise. J Clin Invest. 1975, 56: 1210-1230.
67.Кирюхина ЛД, Кузнецова ВК, Аганезова ЕС, Яковлева НГ, Каменева МЮ. - Метод импульсной осциллометрии в диагностике нарушений механики дыхания. Пульмонология. 2000, 2: 31-36.
68.Пашкова ТЛ, Чикина СЮ, Чучалин АГ. - Импульсная осциллометрия в оценке респираторной механики. Сборник тезисов 15-го Национального конгресса по болезням органов дыхания. Москва, 29 ноября-2 декабря 2005 г. Пульмонология. 2005, приложение: 216 (799).
69.Bohadana AB, Peslin R, Megherbi SE, et al. - Dose-response slope of forced oscillation and forced expiratory parameters in bronchial challenge testing. Eur Respir J. 1999, 13: 295-300.
70.Schmekel B, Smith HJ. - The diagnostic capacity of forced oscillation and forced expiration techniques in identifying asthma by isocapnic hyperpnoea of cold air. Eur Respir J. 1997, 10: 2243-2249.
71.Неклюдова ГВ, Черняк АВ. - Импульсная осциллометрия в оценке провокационного теста. Сборник тезисов 15-го Национального конгресса по болезням органов дыхания. Москва, 29 ноября-2 декабря 2005 г. Пульмонология. 2005, приложение: 213 (785).
72.Goldman MD, Carter R, Klein R, et al. - Within- and between-day variability of respiratory impedance, using impulse oscillometry in adolescent asthmatics. Pediatr Pulmonol. 2002, 34: 312-319.
73.Vink GR, Arets HG, van der Laag J, et al. - Impulse oscillometry: A measure for airway obstruction. Pediatr Pulmonol. 2003, 35: 214-219.
74.Johnson BD, Beck KC, Jorge Zeballos R, Weisman IM. - Advances in Pulmonary Laboratory Testing. Chest. 1999, 116: 1377-1387.
75.Skloot G, Permutt S, Togias A. - Airway hyperresponsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration. J Clin Invest. 1995, 96: 2393-2403.
76.Lebecque P, Stanescu D. - Respiratory resistance by the forced oscillation technique in asthmatic children and cystic fibrosis patients. Eur Respir J 1997, 10: 891-895.
77.Pasker HG, Schepers R, Clement J, et al. - Total respiratory impedance measured by means of the forced oscillation technique in subjects with and without respiratory complaints. Eur Respir J 1996, 9: 131-139.
78.Gibson GJ, Pride NB. - Lung distensibility: The static pressure-volume curve of the lungs and its use in clinical assessment. Br J Dis Chest. 1976, 70: 143-184.
79.Woolcock AJ, Vincent JN, Macklem PT. - Frequency dependence of compliance as a test for obstruction in the small airways. J Clin Invest. 1969, 48: 1097-1105.
80.American Thoracic Society. Lung Function Testing: Selection of Reference Values and Interpretative Strategies. Am Rev Respir Dis 1991, 144: 1202-1218.
81.Quanjer PH. - Standardized Lung Function Testing. Bull Eur Physiopathol. 1983, 19: suppl. 5, 22-27.
82.Pellegrino R, Viegi G, Brusasco V, Crapo RO, Burgos F, Casaburi R, Coates A, van der Grinten CPM, Gustafsson P, Hankinson J, Jensen R, Johnson DC, MacIntyre N, McKay R, Miller MR, Navajas D, Pedersen OF, Wanger J. - Interpretative strategies for lung function tests. Eur Respir J. 2005, 26: 948-968.
83.Hankinson JL, Odencratz JR, Fedan KB. - Spirometric reference values from a sample of the general US population. Am J Respir Crit Care Med. 1999, 159: 179 - 187.
84.Hardie JA, Buist AS, Vollmer WM, Ellingsen I, Bakke PS, Morkve O. - Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. Eur Respir J. 2002, 20: 1117 - 1122.
85.Stocks J, Quanjer PH. - Reference values for residual volume, functional residual capacity and total lung capacity. Eur Respir J. 1995, 8: 492 - 506.
86.McCarthy DS, Craig DB, Cherniak RM - Intraindividual variability in maximal expiratory flow-volume and closing volume in asymptomatic subjects. Am Rev Respir Dis. 1975, 112: 407-411.
87.Wise RA, Connett J, Kurnow K, et al. - Selection of spirometric measurements in a clinical trial, the Lung Health Study. Am J Respir Crit Care Med. 1995, 151: 675-681.
88.Wang ML, McCabe L, Petsonk EL, et al. - Weight gain and longitudinal changes in lung function in steel workers. Chest. 1997, 111: 1526-1532.
89.American Thoracic Society. Single breath carbon monoxide diffusing capacity (transfer factor): Recommendations for a standard technique. Am Rev Respir Dis 1987; 136:1299.
90.American Thoracic Society. Single-breath carbon monoxide diffusing capacity (transfer factor): Recommendations for a standard technique 1995 update. Am J Respir Crit Care Med 1995; 152:2185.
91.Morrison, NJ, Abboud, RT, Ramadan, F, et al. Comparison of DLCO and pressure-volume curves in detecting emphysema. Am Rev Respir Dis 1989; 139:1179.
92.Gould, GA, Redpath, AT, Ryan, M, et al. Lung CT density correlates with measurements of airflow limitation and diffusing capacity. Eur Respir J 1991; 4:141.
93.Stewart, RI. Carbon monoxide diffusing capacity in asthmatic patients with mild airflow limitation. Chest 1988; 94:332.
94.DoPico, GA, Wiley, AL Jr, Rao, P, Dickie, HA. Pulmonary reaction in upper mantle radiation therapy for Hodgkin's disease. Chest 1979; 75:688.
95.Luursema, PB, Star-Kroesen, MA, VanDer Mark, THW, et al. Bleomycin-induced changes in the carbon monoxide transfer factor of the lungs and its components. Am Rev Respir Dis 1983; 128:880.
96.Crawford, SW, Pepe, M, Lin, D, et al. Abnormalities of pulmonary function tests after marrow transplantation predict nonrelapse mortality. Am J Respir Crit Care Med 1995; 152:690.
97.Mitchell, DM, Fleming, J, Pinching, AJ, et al. Pulmonary function in human immunodeficiency virus infection. Am Rev Respir Dis 1992; 146:745.
98.Nieman, RB, Fleming, J, Coker, RJ, et al. Reduced carbon monoxide transfer factor (TLCO) in human immunodeficiency virus type I (HIV-I) infection as a predictor for faster progression to AIDS. Thorax 1993; 48:481.
99.Watters, LC, King, TE, Schwartz, MI, et al. A clinical, radiographic, and physiologic scoring system for the longitudinal assissment of patients with idiopathic pulmonary fibrosis. Am Rev Respir Dis 1986; 133:97.
100.Helmers, RA, Dayton, CS, Burmeister, LF, Hunninghake, GW. Determinants of progression in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1994; 149:444.
101.Fernandez-Bonetti, P, Lupi-Herrera, E, Martinez-Guerra, ML, et al. Peripheral airways obstruction in idiopathic pulmonary artery hypertension. Chest 1983; 83:732.
102.Tashkin, DP, Clements, PJ, Wright, RS, et al. Interrelationships between pulmonary and extrapulmonary involvement in systemic sclerosis. Chest 1994; 105:489.
103.Hills, EA, Geary, M. Membrane diffusing capacity and pulmonary capillary volume in rheumatoid disease. Thorax 1980; 35:851.
104.American Medical Association. Guides to the Evaluation of Permanent Impairment, 2d ed, American Medical Association, Chicago, 1984, p. 86.
105.American Thoracic Society. Evaluation of impairment/disability secondary to respiratory disorders. Am Rev Respir Dis 1986; 133:1205.
106.Miller, A, Thornton, JC, Warshaw, R, et al. Single breath diffusing capacity in a representative sample of the population of Michigan, a large industrial state. Am Rev Respir Dis 1983; 127:270.
107.Rijcken, B, Schouten, JP, Xu, X, et al. Airway hyperresponsiveness to histamine associated with accelerated decline in FEV1. Am J Respir Crit Care Med 1995; 151:1377.
108.Kitaichi, M, Nishimura, K, Itoh, H, Izumi, T. Pulmonary lymphangioleiomyomatosis: A report of 46 patients including a clinicopathologic study of prognostic factors. Am J Respir Crit Care Med 1995; 151:527.
109.Sansores, RH, Abboud, RT, Kennell, C, Haynes, N. The effect of menstruation on the pulmonary carbon monoxide diffusing capacity. Am J Respir Crit Care Med 1995; 152:381.
110.Sansores, RH, Pare, PD, Abboud, RT. Acute effect of cigarette smoking on the carbon monoxide diffusing capacity of the lung. Am Rev Respir Dis 1992; 146:951.
111.Sansores, RH, Pare, P, Abboud, RJ. Effect of smoking cessation on pulmonary carbon monoxide diffusing capacity and capillary blood volume. Am Rev Respir Dis 1992; 146:959.
112.Crapo, RO, Morris, AH. Standardized single breath normal values for carbon monoxide diffusing capacity. Am Rev Respir Dis 1981; 123:185.
113.Johnson, DC. Importance of adjusting carbon monoxide diffusing capacity (DLCO) and carbon monoxide transfer coefficient (KCO) for alveolar volume. Respir Med 2000; 94:28.
114.Kanengiser, LC, Rapoport, DM, Epstein, H, Goldring, RM. Volume adjustment of mechanics and diffusion in interstitial lung disease. Chest 1989; 96:1036.
115.Kangalee, KM, Abboud, RT. Interlaboratory and intralaboratory variability in pulmonary function testing. A 13 year study using a normal biologic control. Chest 1992; 101:88.
116.Mushtaq, M, Hayton, R, Watts, T, et al. An audit of pulmonary function laboratories in the West Midlands. Respir Med 1995; 89:263.
117.Hathaway, EH, Tashkin, DP, Simmons, MS. Intraindividual variability in serial measurement of DLCO and alveolar volume over one year in eight healthy subjects using three independent measuring systems. Am Rev Respir Dis 1989; 140:1818.
118.European Respiratory Society. Standardization of the measurement of transfer factor (diffusing capacity). Eur Respir J 1993; 6(Suppl 16):41.
119.Mead J, Loring SH: Analysis of volume displacement and length changes of the diaphragm during breathing. J Appl Physiol 53:750-755, 1982.
120.Severinghaus JW, Stupfel M: Alveolar dead space as an index of distribution of blood flow in pulmonary capillaries. J Appl Physiol 10:335-348, 1957.
121.Mellemgaard K: The alveolar-arterial oxygen difference: size and components in normal man. Acta Physiol Scand 67:10-20, 1966.
122.West JB: Ventilation-perfusion inequality and overall gas exchange in computer models of the lung. Respir Physiol 7:88-110, 1969.
123.West JB: Causes of carbon dioxide retention in lung disease. N Engl J Med 284:1232-1236, 1971.
124.Lilienthal JL Jr, Riley RL, Premmel DD, et al: An experimental analysis in man of the oxygen pressure gradient from alveolar air to arterial blood during rest and exercise at sea level and at altitude. Am J Physiol 147:199-216, 1946.
125.Riley RL, Cournand A: Analysis of factors affecting partial pressures of oxygen and carbon dioxide in gas and blood of lungs: theory. J Appl Physiol 4:77-101, 1951.
126.Bryan AC, Bentivoglio LG, Beerel F, et al: Factors affecting regional distribution of ventilation and perfusion in the lung. J Appl Physiol 19:395-402, 1964.
127.Wagner HN Jr, Sabiston DC Jr, Iio M, et al: Regional pulmonary blood flow in man by radioisotope scanning. JAMA 187:601-603, 1964.
128.Wagner PD, Saltzman HA, West JB: Measurement of continuous distributions of ventilation-perfusion ratios: Theory. J Appl Physiol 36:588-599, 1974.
129.Hansen JE, Clausen JL, Levy SE, et al: Proficiency testing materials for pH and blood gases: The California Thoracic Society experience. Chest 89:214-217, 1986.
130.Mohler JG, Collier CR, Brandt W, et al: Blood gases. In Clausen JL (ed): Pulmonary Function Testing Guidelines and Controversies: Equipment, Methods, and Normal Values. Orlando, FL: Grune & Stratton, 1984, pp 223-258.
131.Morris AH, Kanner RE, Crapo RO, et al: Blood Gas Analysis (2nd ed). Salt Lake City: Intermountain Thoracic Society, 1984.
132.Van Kampen EJ, Zijlstra WG: Standardization of hemoglobinometry. II. The hemoglobin cyanide method. Clin Chim Acta 6:538-544, 1961.
133.McQuitty JC, Lewiston NJ: Pulmonary function testing of children. In Clausen JL (ed): Pulmonary Function Testing Guidelines and Controversies: Equipment, Methods and Normal Values. Orlando, FL: Grune & Stratton, 1982, pp 321-330
134.Mendelson Y, Kent J, Shaharian A, et al: Evaluation of the Datascope Accusat pulse oximeter in healthy adults. J Clin Monit 4:59-63, 1988
135.Chapman KR, D'Urzo A, Rebuck AS: The accuracy and response characteristics of a simplified ear oximeter. Chest 83:860-864, 1983.
136.Eichorn J, Cooper J, Cullen D, et al: Standards for patient monitoring during anaesthesia at Harvard Medical School. JAMA 256:1017-1020, 1986.
137.Thiele FA, van Kempen LH: A micro method for measuring the carbon dioxide release by small skin areas. Br J Dermatol 86:463-471, 1972.
138.Carter R, Banham SW: Use of transcutaneous oxygen and carbon dioxide tensions for assessing indices of gas exchange during exercise testing. Respir Med 94:350-355, 2000.
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Физическая нагрузка требует существенного напряжения и тесного взаимодействия основных физиологических механизмов, которые делают способными сердечно-сосудистую и респираторную системы поддерживать возрастающие метаболические потребности организма. Обе системы в этом случае находятся в состоянии стресса, и способность адекватно реагировать на этот стресс является показателем их физиологического здоровья и функциональной полноценности. Хорошо известно, что и вентиляция и сердечный выброс повышаются по мере возрастания скорости метаболизма. Адекватная оценка функционального состояния системы транспорта газов, необходимых для поддержания тканевого (клеточного) дыхания очень важна, так как при многих патологических состояниях функционирование этой системы нарушается.
type: dkli00113
Дата добавления: 2015-01-18 | Просмотры: 1274 | Нарушение авторских прав
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