АкушерствоАнатомияАнестезиологияВакцинопрофилактикаВалеологияВетеринарияГигиенаЗаболеванияИммунологияКардиологияНеврологияНефрологияОнкологияОториноларингологияОфтальмологияПаразитологияПедиатрияПервая помощьПсихиатрияПульмонологияРеанимацияРевматологияСтоматологияТерапияТоксикологияТравматологияУрологияФармакологияФармацевтикаФизиотерапияФтизиатрияХирургияЭндокринологияЭпидемиология

ЗАКЛЮЧЕНИЕ. За последние 10 лет произошли существенные изменения в понимании патогенетических процессов, лежащих как в основе эмфиземы

Прочитайте:
  1. В ЗАКЛЮЧЕНИЕ
  2. ЗАКЛЮЧЕНИЕ
  3. ЗАКЛЮЧЕНИЕ
  4. ЗАКЛЮЧЕНИЕ
  5. ЗАКЛЮЧЕНИЕ
  6. ЗАКЛЮЧЕНИЕ
  7. ЗАКЛЮЧЕНИЕ
  8. ЗАКЛЮЧЕНИЕ
  9. ЗАКЛЮЧЕНИЕ
  10. ЗАКЛЮЧЕНИЕ

За последние 10 лет произошли существенные изменения в понимании патогенетических процессов, лежащих как в основе эмфиземы, так и в разработке новых подходов к ведению больных. Внедрение новых методов лучевой диагностики позволяет устанавливать диагноз эмфиземы уже на ранних стадиях болезни до появления клинических проявлений. Современные лечебные технологии дают возможность уменьшить симптомы заболевания, улучшить качество и продолжительность жизни пациентов с эмфиземой легких.

СПИСОК ЛИТЕРАТУРЫ

1.National Heart Lung and Blood Institute. The definition of emphysema. Report of a Division of Lung Diseases workshop.// Am Rev Respir Dis 1985;132:182 - 185.

2.Mason RJ, Murray JF, Broaddus VC, Nadel JA. Textbook of Respiratory Medicine.// Fourth Edition, Elsevier inc., USA 2005, Vol 1. P 1117.

3.Hayashi S, Hogg JC. Adenovirus infections and lung disease //Curr Opin Pharmacol. 2007 Apr 17

4.Theegarten D, Mogilevski G, Anhem O, et al. The role of Chlamydia in the pathogenesis of pulmonary emphysema// Virchows Arch 2000;437:190 - 3

5.Martinez FJ, Curtis JL, Sciurba F. Gender Differences in Severe Pulmonary Emphysema// Am J Respir Crit Care Med. 2007 Apr 12;

6. Изаксон Э. О патолого-анатомических изменениях легочных сосудов при эмфизематозном процессе в легких.// Пульмонология, 2005 4б С.41-52

7.Voelkel N. F., Vandivier R. W, Tuder R. M.Vascular endothelial growth factor in the lung //Am J Physiol Lung Cell Mol Physiol, February 1, 2006; 290(2): L209 - L221

8.Santos S, Peinado VI, Ramirez J et al. Enhanced expression of vascular endothelial growth factor in pulmonary arteries of smokers and patients with moderate chronic obstructive pulmonary disease.//Am J Respir Crit Care Med (2003) 167: 1250-1256

9.Kranenburg A Rl. Enhanced bronchial expression of vascular endothelial growth factor and receptors (Flk-1 and Flt-1) in patients with chronic obstructive pulmonary disease // Thorax 2005;60:106-113

10.Tudern RM, Zhen L, Cho CY. Oxidative Stress and Apoptosis Interact and Cause Emphysema Due to Vascular Endothelial Growth Factor Receptor Blockade.// Am J of Respir Cell and Molec Biol. 2003.Vol. 29, pp. 88-97

11.Harris WH, Chillingworth FP. The experimental production in dogs of emphysema with associated asthmatic syndrome by means of an intratracheal ball valve.// J Exp Med 1919;30:75 - 85.

12.Laurell CB, Erickson S. The electrophoretic a1-globulin pattern of serum in a1-antitrypsin deficiency.// Scan J Clin Lab Invest 1963;15:132 - 140

13.Gross P, Babjak M, Tolker E, et al. Enzymatically produced pulmonary emphysema: A preliminary report.//J Occup Med 1964; 6:481-484

14.Mercer R., Crapo J. D. Structural changes in elastic fibers after pancreatic elastase administration in hamsters. //J. Appl. Physiol. 1992; 72: 1473-1479

15.Orsos F.: Au Uber das elastische Gerauust der normalen und der emphysematosen Lunge.// Pathol. Anat. 41: 95-121, 1907.

16.Hogg JC, Senior RM Chronic obstructive pulmonary disease: Pathology and biochemistry of emphysema// Thorax 2002;57:830-834

17.American Thoracic Society. Standards for the Diagnosis and Management of Individuals with Alpha-1 Antitrypsin Deficiency.// Am. J. Respir. Crit Care Med. 2003;168: 818-900

18.The Alpha 1-Antitrypsin Deficiency Registry Study Group. Survival and FEV1 decline in individuals with severe deficiency of alpha 1-antitrypsin. Am. J. Respir Criti Care Med. 1998; 158:49-59

19. Carp H., Miller F., Hoidal J.R., Janoff A. Potential mechanism of emphysema: alpha 1-proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity.// Proc. Natl. Acad. Sci. USA. 1982; 79: 2041 - 2045.

20.Taggart C., Cervantes-Laurean D., Kim G. Oxidation of either Methionine 351 or Methionine 358 in 1-Antitrypsin Causes Loss of Anti-neutrophil Elastase Activity. J. Biol. Chem. 2000; 275 (35): 27258-27265.

21.Finlay, GA, O’Driscoll, LR, Russell, KJ, et al: Matrix metalloproteinase expression and production by alveolar macrophages in emphysema.// Am. J. Respir. Crit. Care Med., Volume 156, Number 1, July 1997, 240-247

22.Vernooy J, Lindeman J H, Jacobs JA: Increased Activity of Matrix Metalloproteinase-8 and Matrix Metalloproteinase-9 in Induced Sputum From Patients With COPD// Chest. 2004;126:1802-1810

23.Imai K, Dalal S, Chen E Human Collagenase (Matrix Metalloproteinase-1) Expression in the Lungs of Patients with Emphysema// Am. J. Respir. Crit. Care Med., Volume 163, Number 3, March 2001, 786-791

24.Selman M, Cisneros-Lira J, Gaxiola M et al: Matrix metalloproteinases inhibition attenuates tobacco smoke-induced emphysema in guinea pigs// Chest (2003) 123: 1633-1641.

25.Beeh KM, Beier J, Kornmann O, Buhl R Sputum matrix metalloproteinase-9, tissue inhibitor of metalloprotinease-1 and their molar ratio in patients with chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and healthy subjects.// Respir Med 97(2003): 634-639

26.Higashimoto Y, Yamagata Y Increased serum concentrations of tissue inhibitor of metalloproteinase-1 in COPD patients// Eur Respir J. 2005 May;25(5):885-90.

27. Vignola A, Riccobono M, Mirabella A. Sputum Metalloproteinase-9/Tissue Inhibitor of Metalloproteinase-1 Ratio Correlates with Airflow Obstruction in Asthma and Chronic Bronchitis //Am. J. Respir. Crit. Care Med., Volume 158, Number 6, December 1998, 1945-1950

28.Joyce E. Rundhaug Matrix metalloproteinases and angiogenesis// J. Cell. Mol. Med. Vol 9, No 2, 2005 pp. 267-285

29.Russell RE, Thorley A, Culpitt SV et al. Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases// Am J Physiol Lung Cell Mol Physiol 2002;283:867 - 873.

30. Takeyabu K, Betsuyaku T, Nishimura M et al. Cysteine proteinases and cystatin C in bronchoalveolar lavage fluid from subjects with subclinical emphysema// Eur Respir J 1998;12:1033 - 1039

31.Wang Z, Zheng T, Zhu Z et al. Interferon gamma induction of pulmonary emphysema in the adult murine lung// J Exp Med 2000;192:1587 - 1600

32.Henson P.M., Vandivier RW, Douglas S.I. Cell Death, Remodeling, and Repair in Chronic Obstructive Pulmonary Disease?// The Proceedings of the American Thoracic Society (2006)3:713-717

33.Fang KC, Wolters PJ, Steinhoff M, et al. Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta.// J Immunol 1999;162:5528 - 35

34.Kucich U, Rosenbloom JC, Abrams WR, et al.: Transforming growth factor-beta stabilizes elastin mRNA by a pathway requiring active Smads, protein kinase C-delta and p38.// Am J Respir Cell Mol Biol 2002;26:183 - 8

35.Bonniaud P, Kolb M, Galt T et al: Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis.//J Immunol 2004;173:2099 - 2108

36.Pons R, Sauleda J., Noguera A. et al: Decreased macrophage release of TGF-бета and TIMP-1 in chronic obstructive pulmonary disease // Eur. Respir. J., July 1, 2005; 26(1): 60 - 66

37.Aoshiba K, Nagai A. Differences in airway remodeling between asthma and chronic obstructive pulmonary disease.//Clin Rev Allergy Immunol 2004;27:35 - 43

38.Hodge S, Hodge G, Scicchitano R et al. Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells.// Immunol Cell Biol. 2003;81:289 - 296.

39.Vandivier RW, Fadok VA, Hoffmann PR et al: Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis.// J Clin Invest. 2002;109:661 - 670

40.Vlanovich G, Russel ML, Mercer RR, Crapo JD. Cellular and Connective Tissue Changes in Alveolar Septal Walls in Emphysema //Am. J. Respir. Crit. Care Med., Vol 160, Number 6, 1999, 2086-2092

41.Massaro GD, Radaeva S, Clerch LB, Massaro D. Lung alveoli: endogenous programmed destruction and regeneration// Am J Physiol Lung Cell Mol Physiol 2002.283: 305-309

42.Barnes P. J., Stockley R. A. COPD: current therapeutic interventions and future approaches //Eur Respir J 2005; 25:1084-1106

43.Stein J, Fenigstein H. Pathological anatomy of hunger disease.// In: Winick M, editor. Hunger disease: studies by the Jewish physicians in the Warsaw Ghetto: current concepts in nutrition. New York: John Wiley & Sons; 1979. p. 207 - 211

44.Kerr JS, Riley DJ, Lanza-Jacoby S, et al. Nutritional emphysema in the rat // Am Rev Respir Dis 1985;131:644 - 650

45.Coxson H., Ida H. Chan T., Mayo J Early Emphysema in Patients with Anorexia Nervosa// Am J Respir and Crit Care Med 2004;Vol 170. pp. 748-752

46.Patel BD, Loo WJ, Tasker AD et al. Smoking related COPD and facial wrinkling: is there a common susceptibility? Thorax. 2006 Jul;61(7):568-671

47.Uppaluri R, Mitsa T, Sonka M et al. Quantification of pulmonary emphysema from lung computed tomography images.// Am J Respir Crit Care Med 1997;156:248 - 254

48.Sanders C, Nath PH, Bailey W. Detection of emphysema with computed tomography: correlation with pulmonary function tests and chest radiography.// Invest Radiol 1988;23:262 - 266

49.Власов П.В. Лучевая диагностика заболеваний органов грудной полости// «Видар», 2006, стр.65-77

50.Morgan MDL: Detection and quantification of pulmonary emphysema by computed tomography: a window of opportunity// Thorax 1992;47:1001 - 1004

51.Gevenois PA, de Maertelaer V, De Vuyst P et al.: Comparison of computed density and macroscopic morphometry in pulmonary emphysema.// Am J Respir Crit Care Med 1995;152:653 - 657

52.Parr D. G., Dawkins P. A., Stockley R. A. Computed tomography: a new gold standard for the clinical assessment of emphysema//Am. J. Respir. Crit. Care Med., October 15, 2006; 174(8): 954 - 954

53.Watz H, Breithecker A, Rau W. Micro-CT of the Human Lung: Imaging of Alveoli and Virtual Endoscopy of an Alveolar Duct in a Normal Lung and in a Lung with Centrilobular Emphysema - Initial Observations// Radiology 2005;236:1053-1058

54.Chapman K.R., Stockley R.A., Dawkins C. et al. Augmentation therapy for альфа1-antitrypsin deficiency: a meta-analysis of randomized and non-randomized clinical studies.// Eur. Respir. J. 2005; 26 (49): 288

55.Wencker M., Fuhrmann B., Banik N. et al. Longitudinal follow-up of patients with alpha(1)-protease inhibitor deficiency before and during therapy with IV alpha(1)-protease inhibitor.// Chest. 2001; 119:737-744.

56.Lieberman J. Augmentation therapy reduces frequency of lung infections in antitrypsin deficiency: a new hypothesis with supporting data.// Chest 2000; 118:1480 - 1485.

57.Troosters T, Gosselink R, Decramer M. Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial.// Am J Med 2000;109:207 - 212.

58.Finnerty JP, Keeping I, Bullough I, Jones J: The effectiveness of outpatient pulmonary rehabilitation in chronic lung disease: randomized controlled trial// Chest 2001; 119: 1705-1710

59.Martinez F, Foster G, Curtis J. Predictors of Mortality in Patients with Emphysema and Severe Airflow Obstruction// American Journal of Respiratory and Critical Care Medicine Vol 173. pp. 1326-1334, (2006)

60.Celli BR, Cote CG, Marin JM et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease.// N Engl J Med 2004; 350:1005 - 1012

61.Kanner RE, Renzetti AD, Stanish WM et al. Predictors of survival in subjects with chronic airflow limitation// Am J Med 1983;74:249 - 255.

62.Nikoladze G.D. Functional results of surgery for bullous emphysema.// Chest 101: 119-122, 1992

63.Brantigan O, Mueller E. Surgical treatment of pulmonary emphysema.// Am Surg 1957. 23,789-804.

64.Cooper, JD, Trulock, EP, Triantafillou, AN, et al. Bilateral pneumectomy (volume reduction) for chronic obstructive pulmonary disease.// J Thorac Cardiovasc Surg (1995) 109,106-116.

65.Meyers BF, Yusen RD, Guthrie TJ, et al: Results of lung volume reduction surgery in patients meeting a national emphysema treatment trial high-risk criterion. //J Thorac Cardiovasc Surg 2004. 127:829-835

66.Tutic M, Lardinois D, Imfeld S.: Lung-Volume Reduction Surgery as an Alternative or Bridging Procedure to Lung Transplantation.// Ann Thorac Surg 2006; 82:208-213.

67.Wan IY, Toma TP, Geddes DM. Bronchoscopic Lung Volume Reduction for End-Stage Emphysema Report on the First 98 Patients// Chest. 2006;129:518-526

68.Meyers BF, Patterson GA Chronic obstructive pulmonary disease. 10: Bullectomy, lung volume reduction surgery, and transplantation for patients with chronic obstructive pulmonary disease// Thorax. 2003 Jul;58(7):634-8

document:

$pr:

version: 01-2007.1

codepage: windows-1251

type: klinrek

id: kli3121071

: 08.3. БРОНХИАЛЬНАЯ АСТМА

meta:

author:

fio[ru]: А.В. Емельянов, Б.А. Черняк, Н.П. Княжеская, М.О. Потапова, А.С. Белевский

codes:

next:

type: dklinrek

code: III.III

type: dkli00023


Дата добавления: 2015-01-18 | Просмотры: 1108 | Нарушение авторских прав



1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 | 114 | 115 | 116 | 117 | 118 | 119 | 120 | 121 | 122 | 123 | 124 | 125 | 126 | 127 | 128 | 129 | 130 | 131 | 132 | 133 | 134 | 135 | 136 | 137 | 138 | 139 | 140 | 141 | 142 | 143 | 144 | 145 | 146 | 147 | 148 | 149 | 150 | 151 | 152 | 153 | 154 | 155 | 156 | 157 | 158 | 159 | 160 | 161 | 162 | 163 | 164 | 165 | 166 | 167 | 168 | 169 | 170 | 171 | 172 | 173 | 174 | 175 | 176 | 177 | 178 | 179 | 180 | 181 | 182 | 183 | 184 | 185 | 186 | 187 | 188 | 189 | 190 | 191 | 192 | 193 | 194 | 195 | 196 | 197 | 198 | 199 | 200 | 201 | 202 | 203 | 204 | 205 | 206 | 207 | 208 | 209 | 210 | 211 | 212 | 213 | 214 | 215 | 216 | 217 | 218 | 219 | 220 | 221 | 222 | 223 | 224 | 225 | 226 | 227 | 228 | 229 | 230 | 231 | 232 | 233 | 234 | 235 | 236 | 237 | 238 | 239 | 240 | 241 | 242 | 243 | 244 | 245 | 246 | 247 | 248 | 249 | 250 | 251 | 252 | 253 | 254 | 255 | 256 | 257 | 258 | 259 | 260 | 261 | 262 | 263 | 264 | 265 | 266 | 267 | 268 | 269 | 270 | 271 | 272 | 273 | 274 | 275 | 276 | 277 | 278 | 279 | 280 | 281 | 282 | 283 | 284 | 285 | 286 | 287 | 288 | 289 | 290 | 291 | 292 | 293 | 294 | 295 | 296 | 297 | 298 | 299 | 300 | 301 | 302 | 303 | 304 | 305 | 306 | 307 | 308 | 309 | 310 | 311 | 312 | 313 | 314 | 315 | 316 | 317 | 318 | 319 | 320 | 321 | 322 | 323 | 324 | 325 | 326 | 327 | 328 | 329 | 330 | 331 | 332 | 333 | 334 | 335 | 336 | 337 | 338 | 339 | 340 | 341 | 342 | 343 | 344 | 345 | 346 | 347 | 348 | 349 | 350 | 351 | 352 | 353 | 354 | 355 | 356 | 357 | 358 | 359 | 360 | 361 | 362 | 363 | 364 | 365 | 366 | 367 | 368 | 369 | 370 | 371 | 372 | 373 | 374 | 375 | 376 | 377 | 378 | 379 | 380 | 381 | 382 | 383 | 384 | 385 | 386 | 387 | 388 | 389 | 390 | 391 | 392 | 393 | 394 | 395 | 396 | 397 | 398 | 399 | 400 | 401 | 402 | 403 | 404 | 405 | 406 | 407 | 408 | 409 | 410 | 411 | 412 | 413 | 414 | 415 | 416 | 417 | 418 | 419 | 420 | 421 | 422 | 423 | 424 | 425 | 426 | 427 | 428 | 429 | 430 | 431 | 432 | 433 | 434 | 435 | 436 | 437 | 438 | 439 | 440 | 441 | 442 | 443 | 444 | 445 | 446 | 447 | 448 | 449 | 450 | 451 | 452 | 453 | 454 | 455 | 456 | 457 | 458 | 459 | 460 | 461 | 462 | 463 | 464 | 465 | 466 | 467 | 468 | 469 | 470 | 471 | 472 | 473 | 474 | 475 | 476 | 477 | 478 | 479 | 480 | 481 | 482 | 483 | 484 | 485 | 486 | 487 | 488 | 489 | 490 | 491 | 492 | 493 | 494 | 495 | 496 | 497 | 498 | 499 | 500 | 501 | 502 | 503 | 504 | 505 | 506 | 507 | 508 | 509 | 510 | 511 | 512 | 513 | 514 | 515 | 516 | 517 | 518 | 519 | 520 | 521 | 522 | 523 | 524 | 525 | 526 | 527 | 528 | 529 | 530 | 531 | 532 | 533 | 534 | 535 | 536 | 537 | 538 | 539 | 540 | 541 | 542 | 543 | 544 | 545 | 546 | 547 | 548 | 549 | 550 | 551 | 552 | 553 | 554 | 555 | 556 | 557 | 558 | 559 | 560 | 561 | 562 | 563 | 564 | 565 | 566 | 567 | 568 | 569 | 570 | 571 | 572 | 573 | 574 | 575 | 576 | 577 | 578 | 579 | 580 | 581 | 582 | 583 | 584 | 585 | 586 | 587 | 588 | 589 | 590 | 591 | 592 | 593 | 594 | 595 | 596 | 597 | 598 | 599 | 600 | 601 | 602 | 603 | 604 | 605 | 606 | 607 | 608 | 609 | 610 | 611 | 612 | 613 | 614 | 615 | 616 | 617 | 618 | 619 | 620 | 621 | 622 | 623 | 624 | 625 | 626 | 627 | 628 | 629 | 630 | 631 | 632 | 633 | 634 | 635 | 636 | 637 | 638 | 639 | 640 | 641 | 642 | 643 | 644 | 645 | 646 | 647 | 648 | 649 | 650 | 651 | 652 | 653 | 654 | 655 | 656 | 657 | 658 | 659 | 660 | 661 | 662 | 663 | 664 | 665 | 666 | 667 | 668 | 669 | 670 | 671 | 672 | 673 | 674 | 675 | 676 | 677 | 678 | 679 | 680 | 681 | 682 | 683 | 684 | 685 | 686 | 687 | 688 | 689 | 690 | 691 | 692 | 693 | 694 | 695 | 696 | 697 | 698 | 699 | 700 | 701 | 702 | 703 | 704 | 705 | 706 | 707 | 708 | 709 | 710 | 711 | 712 | 713 | 714 | 715 | 716 | 717 | 718 | 719 | 720 | 721 | 722 | 723 | 724 | 725 | 726 | 727 | 728 | 729 | 730 | 731 | 732 | 733 | 734 | 735 | 736 | 737 | 738 | 739 | 740 | 741 | 742 | 743 | 744 | 745 | 746 | 747 | 748 | 749 | 750 | 751 | 752 | 753 | 754 | 755 | 756 | 757 | 758 | 759 | 760 | 761 | 762 | 763 | 764 | 765 | 766 | 767 | 768 | 769 | 770 | 771 | 772 | 773 | 774 | 775 | 776 | 777 | 778 | 779 | 780 | 781 | 782 | 783 | 784 | 785 | 786 | 787 | 788 | 789 | 790 | 791 | 792 | 793 | 794 | 795 | 796 | 797 | 798 | 799 | 800 | 801 | 802 | 803 | 804 | 805 | 806 | 807 | 808 | 809 | 810 | 811 | 812 | 813 | 814 | 815 | 816 | 817 | 818 | 819 | 820 | 821 | 822 | 823 | 824 | 825 | 826 | 827 | 828 | 829 | 830 | 831 | 832 | 833 | 834 | 835 | 836 | 837 | 838 | 839 | 840 | 841 | 842 | 843 | 844 | 845 | 846 | 847 | 848 | 849 | 850 | 851 | 852 | 853 | 854 | 855 | 856 | 857 | 858 | 859 | 860 | 861 | 862 | 863 | 864 | 865 | 866 | 867 | 868 | 869 | 870 | 871 | 872 | 873 | 874 | 875 | 876 | 877 | 878 | 879 | 880 | 881 | 882 | 883 | 884 | 885 | 886 | 887 | 888 | 889 | 890 | 891 | 892 | 893 | 894 | 895 | 896 | 897 | 898 | 899 | 900 | 901 | 902 | 903 | 904 | 905 | 906 | 907 | 908 | 909 | 910 | 911 | 912 | 913 | 914 | 915 | 916 | 917 | 918 | 919 | 920 | 921 | 922 | 923 | 924 | 925 | 926 | 927 | 928 | 929 | 930 | 931 | 932 | 933 | 934 | 935 | 936 | 937 | 938 | 939 | 940 | 941 | 942 | 943 | 944 | 945 | 946 | 947 | 948 | 949 | 950 | 951 | 952 | 953 | 954 | 955 | 956 | 957 | 958 | 959 | 960 | 961 | 962 | 963 | 964 | 965 | 966 | 967 | 968 | 969 | 970 | 971 | 972 | 973 | 974 | 975 | 976 | 977 | 978 | 979 | 980 | 981 | 982 | 983 | 984 | 985 | 986 | 987 | 988 | 989 | 990 | 991 | 992 | 993 | 994 | 995 | 996 | 997 | 998 | 999 | 1000 | 1001 | 1002 | 1003 | 1004 | 1005 | 1006 | 1007 | 1008 | 1009 | 1010 | 1011 | 1012 | 1013 | 1014 | 1015 | 1016 | 1017 | 1018 | 1019 | 1020 | 1021 | 1022 | 1023 | 1024 | 1025 | 1026 | 1027 | 1028 | 1029 | 1030 | 1031 | 1032 | 1033 | 1034 | 1035 | 1036 | 1037 | 1038 | 1039 | 1040 | 1041 | 1042 | 1043 | 1044 | 1045 | 1046 | 1047 | 1048 | 1049 | 1050 | 1051 | 1052 | 1053 | 1054 | 1055 | 1056 | 1057 | 1058 | 1059 | 1060 | 1061 | 1062 | 1063 | 1064 | 1065 | 1066 | 1067 | 1068 | 1069 | 1070 | 1071 | 1072 | 1073 | 1074 | 1075 | 1076 | 1077 | 1078 | 1079 | 1080 | 1081 | 1082 | 1083 | 1084 | 1085 | 1086 | 1087 | 1088 | 1089 | 1090 | 1091 | 1092 | 1093 | 1094 | 1095 | 1096 | 1097 | 1098 | 1099 | 1100 | 1101 | 1102 | 1103 | 1104 | 1105 | 1106 | 1107 | 1108 | 1109 | 1110 | 1111 | 1112 | 1113 | 1114 | 1115 | 1116 | 1117 | 1118 | 1119 | 1120 | 1121 | 1122 | 1123 | 1124 | 1125 | 1126 | 1127 | 1128 | 1129 | 1130 | 1131 | 1132 | 1133 | 1134 | 1135 | 1136 | 1137 | 1138 | 1139 | 1140 | 1141 | 1142 | 1143 | 1144 | 1145 | 1146 | 1147 | 1148 | 1149 | 1150 | 1151 | 1152 | 1153 | 1154 | 1155 | 1156 | 1157 | 1158 | 1159 | 1160 | 1161 | 1162 | 1163 | 1164 | 1165 | 1166 | 1167 | 1168 | 1169 | 1170 | 1171 |



При использовании материала ссылка на сайт medlec.org обязательна! (0.009 сек.)