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ЛЕЧЕНИЕ МЕЛКОКЛЕТОЧНОГО РАКА ЛЕГКОГОМелкоклеточный рак легкого характеризуется быстрым развитием, ранним интенсивным лимфогенным и гематогенным метастазированием и плохим прогнозом. У 80 - 90% больных диагностируют распространенный опухолевый процесс. Поэтому многие годы мелкоклеточный рак считали «терапевтическим» и противопоказанием к хирургическому лечению. Сочетанное применение комбинированной химиотерапии и лучевой терапии МРЛ давно получило всеобщее признание и подтверждено многочисленными рандомизированными исследованиями [146, 147]. В настоящее время при I - II стадии, особенно неовсяноклеточном морфологическом подтипе МРЛ, возможно хирургическое лечение с последующей полихимиотерапией (до 6 курсов). Некоторые исследователи считают целесообразным проведение неоадъювантной (2 - 4 курса) и адъювантной полихимиотерапии даже при III стадии МРЛ. Пятилетняя выживаемость после комбинированного лечения в сочетании с хирургическим методом при I - II стадии составляет 28 - 36%, лучшие результаты достигаются при отсутствии метастазов в лимфатических узлах (45 - 49%). При III (N2+) стадии сведения противоречивы - более 5 лет переживают от 5 до 40% больных [8, 148 - 152]. Задача лучевой терапии при комбинированном лечении - улучшить локальный контроль. Профилактическое облучение головного мозга показано пациентам с полной ремиссией при исходно ограниченном (I - II стадия) опухолевом процессе [153]. Больным с неоперабельным МРЛ III - IV стадии проводят консервативную противоопухолевую терапию, сочетая химиотерапию с лучевой [8, 154]. Современные методики такого лечения позволяют у 80 - 90% больных получить непосредственный объективно регистрируемый эффект, у 20 - 30% из них - полную регрессию опухоли. Достижение полной клинической ремиссии после основного курса лечения увеличивает выживаемость больных и открывает перспективу излечения.
СПИСОК ЛИТЕРАТУРЫ 1.Давыдов М.И., Аксель Е.М./ Злокачественные новообразования в России и странах СНГ в 2001 г. МИА. Москва, 2003. 293 с. 2.Чиссов В.И., Старинский В.В., Петрова Г.В./ Злокачественные новообразования в России в 2004 году. Москва, 2005, 246 с. 3.Pira E., Pelucchi C., Buffoni L., Palmas A. et al. Cancer mortality in a cohort of asbestos textile workers// Cancer. 2005. 14;92(3).P580-6. 4.Grosche B, Kreuzer M., Kreisheimer M. et al. Lung cancer risk among German male uranium miners: a cohort study, 1946-1998// Br J Cancer. 2006. Nov 6;95(9).P 1280-1287. 5.Subramanian J., Govindan R. Lung cancer in never smokers: a review// Clin Oncol. 2007. Feb 10;25(5).P,561-70. 6.Toh C.K., Gao F., Lim W.T. et al. Differences between small-cell lung cancer and non-small-cell lung cancer among tobacco smokers// Lung Cancer. 2007 Jan 30 (Epub ahead of print). 7.Wakelee H.A., Chang E.T. Gomez S.L. et al. Lung cancer incidence in never smokers// Clin Onkol. 2007, Feb 10;25(5):472-8. 8.Трахтенберг А.Х., Чиссов В.И. Клиническая онкопульмонология. ГЕОТАР Медицина, 2000, 600 с. 9.Cassidi A., Duffy S.W., Myles J.P. et al. Lung cancer risk prediction: a tool for early detection. Int J Cancer., 2007, Jan 1; 120(1): 1-6. 10.Marcus P, Bergstralh E, Fagerstrom R, et al: Lung cancer mortality in Mayo Lung Project: Impact of extended follow up. J Natl Cancer Inst 92:1308-1316, 2000. 11.Bach P, Kelly M, Tate R, et al: Screening for lung cancer: A review of the literature. Chest 123(1 Suppl):72S-82S, 2003. 12.Sone S, Li F, Yang Z, et al: Characteristics of small lung concerns invisible on conventional chest radiography and detected by population based screening using spiral CT. Br J Radiol 73:137-145, 2000. 13.Henschke C.I., Yankelevitz D.F., Libby D.M. et al. Survival of patients with stage I lung cancer detected on CT screening. N Engl. J Med., 2006, Oct 26;355(17):1763-71. 14.Ольховская И.Г. Опухоли легкого. Патологоанатомическая диагностика опухолей человека. Под ред. Н.А.Краевского и др. М., 1982, с. 129-135. 15.The Japan Lung Cancer Society. Classification of Lung Cancer. Tokyo: Kanehara, 2000 16.UICC. TNM classification of malignant tumours, 5th and 6th eds. Geneva: UICC, 1997 and 2002. 17.Полоцкий Б.Е., Тер-Ованесов М.Д. Рак легкого - некоторые аспекты клиники, диагностики и лечения. Русский Медицинский журнал, т.13, 23, с.1520-1531. 18.Grippi M.A. Clinical aspects of lung cancer. Semin Roentgenol 1990; 25:12 - 24 19.Maddison P., Newsom-Davis J., Mills K.R. et al. Favourable prognosis in Lambert-Eaton myasthenic syndrome and smallcell carcinoma. Lancet 1999; 353:117 - 118 20.Croteau D., Owainati A., Dalmau J. et al. Response to cancer therapy in a patient with a paraneoplastic choreiform disorder. Neurology 2001; 57:719 - 722 21.Ищенко Б.И., Бисенков Л.Н., Тюрин И.Е. Лучевая диагностика для торакальных хирургов. Санкт-Петербург, 2001,343 с. 22.Седых С.А., Кашутина Е.И. Анализ результатов КТ, рентгенографии, бронхоскопии в диагностике центрального рака легкого. Дифференциальная диагностика и лечение рака легкого. Пермь, 2004, с. 59-62. 23.Silvestri GA, Tanoue LT, Margolis ML, et al: The noninvasive staging of non-small cell lung cancer: The guidelines. Chest 123(1 Suppl):147S-156S, 2003 24.Седых С.А., Кашутина Е.И., Рубцова Н.А. Перспективы применения компьютерной томографии в ранней диагностике центрального рака легкого. Росс.онкол.журнал, 2007, 1, с. 4- 9. 25.Адасько Е.В. Роль компьютерной томографии в дифференциальной диагностике одиночных шаровидных образований легких. Автореферат дис. На соис. уч. ст. кан.мед.наук, Москва, 2003, 19 с. 26.Седых С.А., Щетинин В.В., Адасько Е.В., Викулова Ю.В. Значение денсетометриии в первичной и уточняющей КТ диагностике опухолей легких и пищевода. Онкология на рубеже ХХI века. М., 1999, с.331-332. 27.Arita T, Kuramitsu T, Kawamura M, et al Bronchogenic carcinoma: incidence of metastasis to normal sized lymph nodes. Thorax 1995;50,1257-1269 28.Fritscher-Ravens A., Bohuslavizki K.H, Brandt L. et al. Mediastinal lymph node involvement in potentially resectable lung cancer: comparison of CT, positron emission tomography, and endoscopic ultrasonography with and without fine-needle aspiration. Chest. 2003 Feb;123(2):442-51. 29.Sioris T., Järvenpää R., Kuukasjärvi P. et al. Comparison of computed tomography and systematic lymph node dissection in determining TNM and stage in non-small cell lung cancer. Eur J Cardiothorac Surg 2003;23:403-408 30.Bradley J, Thorstad WL, Mutic S, Miller TR, Dehdashti F, Siegel BA, Bosch W, Bertrand RJ. Impact of FDG-PET on radiation therapy volume delineation in non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 2004;59:78 - 86. 31.Reed CE, Harpole DH, Posther KE et al. Results of the American College of Surgeons Oncology Group Z0050 trial: the utility of positron emission tomography in staging potentially operable non-small cell lung cancer. J Thorac Cardiovasc Surg 2003;126:1943 - 1951 32.Gupta NC, Rogers JS, Graeber GM et al. Clinical role of F-18 fluorodeoxyglucose positron emission tomography imaging in patients with lung cancer and suspected malignant pleural effusion. Chest 2002;122:1918 - 1924. 33.Vansteenkiste J, Fischer BM, Dooms C, Mortensen J. Positron-emission tomography in prognostic and therapeutic assessment of lung cancer: systematic review. Lancet Oncol 2004;5:531 - 540. 34.Gould MK, Kuschner WG, Rydzak CE, Maclean CC, Demas AN, Shigemitsu H, Chan JK, Owens DK. Test performance of positron emission tomography and computed tomography for mediastinal staging in patients with non-small-cell lung cancer: a meta-analysis. Ann Intern Med 2003;139:879 - 892. 35.Lardinois D, Weder W, Hany TF, et al. Staging of non-small-cell lung cancer with integrated positron-emission tomography and computed tomography. N Engl J Med 2003;348:2500 - 2507. 36.Yi CA, Lee KS, Kim BT. et al. Efficacy of helical dynamic CT versus integrated PET/CT for detection of mediastinal nodal metastasis in non-small cell lung cancer. AJR Am J Roentgenol. 2007 Feb;188(2):318-25. 37.MacManus MP, Hicks RJ, Matthews JP et al. Positron emission tomography is superior to computed tomography scanning for response-assessment after radical radiotherapy or chemoradiotherapy in patients with non-small cell lung cancer. J Clin Oncol 2003;21:1285 - 1292 38.Rolston K.VI, Rodriguez S., Dhilakia N. et al. Pulmonary infections mimicking cancer: a retrospective, three-year review. Support Care Cancer 1997; 5:90 - 95 39.Schreiber G, McCrory DC: Performance characteristics of different modalities for diagnosis of suspected lung cancer. Chest 123:115S-128S, 2003 40.Chin R, McCain TW, Lucia MA, et al: Transbronchial needle aspiration in diagnosing and staging lung cancer. Chest 166:377-381, 2002 41.Toloza E, Harpole L, Detterbeck F, et al: Invasive staging of non-small cell lung cancer: A review of the current evidence. Chest 123(1 Suppl):157S-166S, 2003. 42.Eloubeidi M.A., Tamhane A., Chen V.K., Cerfolio R.J. Endoscopic ultrasound-guided fine-needle aspiration in patients with non-small cell lung cancer and prior negative mediastinoscopy. Ann. Thorac. Surg., 2005, Oct; 80(4): 1231-9. 43.Соколов В.В. Современные возможности эндоскопии в онкологии. Онкология на рубеже ХХI века, материалы международного научного форума, Москва, 1999, с. 361-363. 44.Lam S. Bronchoscopic, photodynamic, and laser diagnosis and therapy of lung neoplasms. Curr Opin Pulm Med 1996;2:271 - 276. 45.Shimizu K., Ikeda N., Tsuboi T., et al. Percutaneous CT-guided fine needle aspiration for lung cancer smaller than 2cm and revealed by ground-glass opacity at CT. Cancer, 2006, Feb;51(2):173-9. 46.Protopapas Z, Westcott JL. Transthoracic needle biopsy of mediastinal lymph nodes for staging lung cancer and other cancers. Radiology 1996; 199:489 - 496 47.Okamoto H, Watanabe K, Nagatomo A, et al: Endobronchial ultrasonography for mediastinal and hilar lymph node metastases of lung cancer. Chest 121:1498-1506, 2002 48.Fritscher-Ravens A, Soehendra N, Schirrow L, et al. Role of transesophageal endosonography-guided fine-needle aspiration in the diagnosis of lung cancer. Chest 2000; 117:339 - 345 49.Wallace MB, Silvestri GA, Sahai AV, et al. Endoscopic ultrasound-guided fine needle aspiration for staging patients with carcinoma of the lung. Ann Thorac Surg 2001; 72:1861 - 1867 50.Hammoud ZT, Anderson RC, Meyers BF, et al: The current role of mediastinoscopy in the evaluation of thoracic disease. J Thorac Cardiovasc Surg 118:894-899, 1999 51.Rusch V. W. Mediastinoscopy: An Endangered Species? Journal of Clinical Oncology, Vol 23, No 33 (November 20), 2005: pp. 8283-8285 52.Jiao J, Magistrelli P, Goldstraw P. The value of cervical mediastinoscopy combined with anterior mediastinotomy in the preoperative evaluation of bronchogenic carcinoma of the left upper lobe. Eur J Cardiothorac Surg 1997; 11:450 - 454 53.Freixinet Gilart J, Garcia PG, de Castro FR, et al. Extended cervical mediastinoscopy in the staging of bronchogenic carcinoma. Ann Thorac Surg 2000; 70:1641 - 1643 54.Martin de Nicolas J., Gomez-Caro Andres A., Moradiellos Dies F.J. et al. Importance of routine mediastinal staging in women with non-small cell lung cancer. Arch. Bronconeumol, 2005, Mar; 41(3):125-9 55.Sahn SA. Malignancy metastatic to the pleura. Clin Chest Med 1998; 19:351 - 361 56.Sears D, Hadju SI. The cytologic diagnosis of malignant neoplasms in pleural and peritoneal effusions. Acta Cytol,1987; 31:87 - 92 57.Graham PH, Gebski VJ, Langlands AO. Radical radiotherapy for early nonsmall cell lung cancer. Int J Radiat Oncol Biol Phys 1995; 31:261 - 266. 58.Бойко А.В., Трахтенберг А.Х. Лучевое и химиолучевое лечение немелкоклеточного рака легкого. В кн. Клиническая онкопульмонология. Трахтенберг А.Х., Чиссов В.И., ГЕОТАР Медицина, 2000, с.394-417. 59.Полоцкий Б.Е., Тер-Ованесов М.Д. Рак легкого - некоторые аспекты клиники, диагностики и лечения. Русский Медицинский журнал, 2005,т.13, 23, с.1520-1531. 60.Pirrker R., Krajnik G., Zochbauer S. et al. Paclitaxel/cisplatin in advanced non-small-cell lung cancer (NSCLC). Ann Oncol. 1995 Oct;6(8):833-5. 61.von Pawel J., Wagner H., Niederle N. et al. Phase II study of paclitaxel and cisplatin in patients with non-small cell lung cancer.Semin Oncol. 1996 Dec;23(6 Suppl 16):47-50. 62.Соколов В.В. Фотодинамическая терапия. Возможности и перспективы. Онкология на рубеже ХХI века, материалы международного научного форума, Москва, 1999, с. 360-361. 63.Van Boxem T., Venmans B., Schramel F. et al. Radiographically occult lung cancer treated with fiberoptic bronchoscopic electrocautery: a pilot study of a simple and inexpensive technique. Eur Respir J 1998; 11:169 - 172. 64.Fujimura S., Sakurada A., Sagawa M. et al. A therapeutic approach to roentgenographically occult squamous cell carcinoma of the lung. Cancer 2000; 89(suppl):2445 - 2448. 65.Deygas N., Froudarakis M., Ozenne G. et al. Cryotherapy in early superficial bronchogenic carcinoma. Chest 2001; 120:26 - 31 66.Ono R, Ikeda S, Suemasu K. Hematoporphyrin derivative photodynamic therapy in roentgenographically occult carcinoma of the tracheobronchial tree. Cancer 1992; 69:1696 - 1701. 67.Furuse K, Fukuoka M, Kato H, et al. A prospective phase II study on photodynamic therapy for centrally located earlystage lung cancer. J lin Oncol 1993; 11:1852 - 1857. 68.Kato H, Okunaka T, Tsuchida T, et al. Analysis of the cost-effectiveness of photodynamic therapy in early stage lung cancer. Diagn Ther ndosc 1999; 6:9 - 16. 69.Patelli M, Lazzari A, Poletti V, et al. Photodynamic laser therapy for the treatment of early-stage bronchogenic carcinoma. Monaldi Arch hest Dis 1999; 54:315 - 318. 70.Radu A, Grosjean P, Fontolliet C, et al. Photodynamic therapy for 101 early cancers of the upper aerodigestive tract, the esophagus, and the bronchi: a single-institution experience. Diagn Ther Endosc 1999; 5:145 - 154. 71.van Rens MT, de la Riviere AB, Elbers HR, et al. Prognostic assessment of 2,361 patients who underwent pulmonary resection for non-small cell lung cancer, stage I, II, and IIIA. Chest 2000; 117:374 - 379. 72.Jassem J, Skokowski J, Dziadziuszko R, Jassem E. et al. Results of surgical treatment of non-small cell lung cancer: validation of the new postoperative pathologic TNM classification. J. Thorac Cardiovasc Surg, 2000, Jun;119(6):1141-6. 73.Naruke T., Tsuchiya R., Kondo H., Asamura H. Prognosis and survival after resection for bronchogenic carcinoma based on the 1997 TNM-staging classification: the Japanese experience. Ann Thorac Surg., 2001, Jun;71(6):1757-8. 74.Garcia-Yuste M, Matilla JM, Duque JL, et al. Surgical treatment of lung cancer: comparative assessment of the staging systems of 1986 and 1997. Results in 500 consecutive patients. Arch Bronconeumol 2001 Jan;37(1):54. 75.Gao Y.S., Zhang D.C., He J., Sun K.L. et al. Diagnosis and surgical treatment for stage I non-small-cell lung cancer. Zhonghua Zhong Liu Za Zhi, 2005, Jan 27(1):52-5. 76.Goya T., Asamura H., Yoshimura H., Kato H. et al. Prognosis of 6644 resected non-small cell lung cancers in Japan: A Japanese lung cancer registry study. Lung Cancer, 2005, Jun 29. 77.Харченко В.П., Кузьмин И.В. Рак легкого. Руководство для врачей. М., Медицина, 1994, 480 с. 78.Зырянов Б.Н., Сиянов В.С., Величко С.А., Макаркин Н.А. Рак легкого. Новые подходы в диагностике и лечении. Томск, 1997, 346 с. 79.Ginsberg RJ, Rice TW, Goldberg M, et al. Extended cervical mediastinoscopy: a single staging procedure for bronchogenic carcinoma of the left upper lobe. Thorac Cardiovasc Surg 1987; 94:673 - 678 80.Jensik R.J. The role of segmental resection of primary lung cancer/ Chest. 1986, v. 89, p. 335. 81.Warren W.H., faber L.P. Segmentectomy versus lobectomy in patients with stage I pulmonary carcinoma. Five-year surgvival and patterns of intrathoracic recurrence. J.Thorac. Cardiovasc. Surg., 1994, v. 107,p.1087-1093. 82.Mezzetti M, Panigalli T, Scarlata P. Prognostic influence of neoplastic involvement of bronchial stump after anatomical lung resection for NSCLC. Minerva Chir. 2001 Dec;56(6):593-8. 83.El-Sherif A., Gooding W.E., Santos R. et al. Outcomes of sublobar resection versus lobectomy for stage I non-small cell lung cancer: a 13-year analysis. Ann Thorac Surg., 2006, Aug;82(2):408-16. 84.Miyazawa M, Shiina T, Kurai M,et al. Assessment of the new TNM classification for resected lung cancer. Kyobu Geka. 2000 Oct;53(11):915-8. 85.Saito Y, Yamakawa Y, Kuriyama M, et al. Evaluation of new TNM lung cancer classification. J Thorac Cardiovasc Surg 2000; 48: 499 - 505. 86.Inoue M., Miyoshi S., Yasumitsu T., Mori T. et al. Surgical results for small cell lung cancer based on the new TNM staging system. Thoracic Surgery Study Group of Osaka University, Osaka, Japan. Ann Thorac Surg. 2000 Nov;70(5):1615-9. 87.Hayashi Y, Tomiyama I, Ishii H. et al. Prognostic assessment of the new UICC TNM classification for resected lung cancer. Kyobu Geka. 2000 Oct;53(11):919-25. 88.Fang D., Zhang D., Huang G. et al. Results of surgical resection of patients with primary lung cancer: a retrospective analysis of 1,905 cases. Ann Thorac Surg. 2001 Oct;72(4):1155-9. 89.Stephens RJ. The role of post-operative radiotherapy in non-small cell lung cancer: a multicentre randomised trial in patients with pathologically staged T1-2 N1-2 M0 disease. MRC Lung Cancer Working Party. Br J Cancer 1996;74:632 - 639. 90.Dautzenberg B, Arriagada R, Chammard A, et al. A controlled study of postoperative radiotherapy for patients with completely resected nonsmall cell lung carcinoma. Cancer 1999; 86:265 - 273. 91.Стариков В.И., Трунов Г.В. Рак легкого. Харьков, 2002, 212 с. 92.Riquet M, Manac’h D, Le Pimpec-Barthes F, et al. Prognostic significance of surgical-pathologic N1 disease in non-small cell carcinoma of the lung. Ann Thorac Surg 1999; 67:1572 - 1576. 93.Depierre A, Milleron B, Moro-Sibilot D, et al. Preoperative chemotherapy followed by surgery compared with primary surgery in resectable stage I (except T1N0), II, and IIIa non-small cell lung cancer. J Clin Oncol 2001; 20:247 - 253. 94.Roberts J, Eustis C, Devore R, et al. Induction chemotherapy increases perioperative complications in patients undergoing resection for non-small cell lung cancer. Ann Thorac Surg 2001; 72:885 - 888. 95.Scott W. J., Howington J., Movsas B. Treatment of Stage II Non-small Cell Lung Cancer. Chest 2003; 123:188 - 201. 96.Jeremic B., Milicic B., Acimovic L., Milisavljevic S. Concurrent Hyperfractionated radiotherapy and low-dose daily carboplatin/paclitaxel with erly-stage (I/II) non-small-cell lung cancer: long-term results of a phase II study. J. Clin.Oncol., 2005, Oct. 1;23(28):6873-80. 97.Xia T. Li H., Sun Q., Wang Y., Fan N. et al. Promising clinical outcome of stereotactic body radiation therapy for patients with inoperable Stage I/II non-small-cell lung cancer. Int. J. Radiat. Oncol. Biol. Phys., 2006, Sep., 1;66(1):117-25. 98.Rice T.W. Blackstone E. H. Radical resections for T4 lung cancer. Surgical Clinics of North America Volume 82, N. 3, June 2002. 99.Detterbeck F.C., Jones D.R., Kernstine K.H., Naunheim K.S. Lung cancer Gnidelines. Chest, 2003, v. 123, N 1, p. 100.Dartevelle P.G., Macchiarini P. Yechnigues of pneumonectomy: sleeve pheumonectomy. Chest Surg Clin North Am, 1999, 9, 407-17. 101.Kawahara K, Shirakusa T. Carinal resection for lung cancer. Kyobu Geka, 2001, Jan;54(1):36-41. 102.Давыдов М.И. Полоцкой Б.Е., Герасимов С.С. Резекция бифуркации трахеи при немелкоклеточном раке легкого. Материалы 3-международной конференции по торакальной хирургии. Москва, 2005, С. 42-43. 103.Харченко В.П., Чхиквадзе В.Д., Гваришвили А.А. Реконструктивные операции в лечении опухолей легких. Материалы 3-международной конференции по торакальной хирургии. Москва, 2005, С. 126-130. 104.Roviaro G., Vergani C., Maciocco M. et al. Tracheal sleeve pneumonectomy: long-term outcome. Lung Cancer., 2006, Apr;52(1):105-10. 105.Politi l., Seanagatta P., Salani A. et al. T4 tracheo-bronchial carcinoma: clinical evaluation of sleeve pneumonectomies. Chir Ital., 2004, Nov-Dec; 56(6):787-91. 106.Бисенков Л.Н., Гришаков С.В., Шалаев С.А. Хирургия рака лёгкого в далеко зашедших стадиях заболевания. СПб., Гиппократ, 1998, 384 с. 107.Bernard A, Bouchot O, Hagry O, Favre JP. Risk analysis and long-term survival in patients undergoing resection of T4 lung cancer. Eur J Cardiothorac Surg. 2001 Aug;20(2):344-9. 108.Tsuchiya R., Asamura H., Kondo H. et al. Extended recection of the left atrium, great vessels, or both for lung cancer. Ann Torac Surg, 1994, 57 (4): 960-5. 109.Hirai T., Yoshida I., Kawashima O., Kamiyoshihara M. et al. T4 lung cancer: surgical indications based on results of surgical treatment Kyobu Geka. 1997 Feb;50(2):106-9 110.Bobbio A., Carbognani P., Grapeggia M. et al. Surgical outcome of combined pulmonary and atrial resection for lung cancer. Thorac cardiovasc Surg., 2004,Jun;52(3):180-2. 111.Ratto GB, Costa R, Vassallo G. et al.Twelve-year experience with left atrial resection in the treatment of non-small cell lung cancer. Ann Thorac Surg. 2004 Jul;78(1):234-7. 112.Брюсов П.Г., Васюкевич А.Г., Фокин А.В. Комбинированные операции в тактике лечения немелкоклеточного рака легкого III стадии. IX Российский онкологический конгресс, 22-24 ноября,Москва 2005, с.167. 113.Doddoli C, Rollet G, Thomas P. et al. Is lung cancer surgery justified in patients with direct mediastinal invasion? Eur J Cardiothorac Surg. 2001 Aug;20(2):339-43. 114.Guggino G, Doddoli C, Barlesi F. et al. Completion pneumonectomy in cancer patients: experience with 55 cases. Eur J Cardiothorac Surg. 2004 Mar;25(3):449-55. 115.Thomas P., Magnan P.E., Moulin G. et al. Extended operation for lung cancer invading the superior vena cava.Eur J Cardiothorac Surg. 1994;8(4):177-82. 116.Watanabe S., Oda M, Tomita Y. et al. Extended resection of the great vessels for primary lung cancer and mediastinal tumor. Kyobu Geka. 1999 Jan;52(1):4-7 117.Xu GC, Rong TH, Lin P. Adjuvant chemotherapy following radical surgery for non-small-cell lung cancer: a randomized study on 70 patients. Chin Med J 2000;113(7):617-620 118.Spaggiari L, Veronesi G, D'Aiuto M, Tosoni A. Superior vena cava reconstruction using heterologous pericardial tube after extended resection for lung cancer. Eur J Cardiothorac Surg. 2004 Sep;26(3):649-51. 119.Suzuki K., Asamura H., Watanabe S., Tsuchiya R. et al. Combined resection of superior vena cava for lung carcinoma: prognostic significance of patterns of superior vena cava invasion. Ann Thorac Surg. 2004 Oct;78(4):1184-9; discussion 1184-9 120.Downey R. J., Rusch V., Hsu F. I. et al. Chest wall resection for locally recurrent breast cancer: Is it worthwhile? J. Thorac. Cardiovasc. Surg. 2000, 119:420-8. 121.Volpino P., Cangemi B, Frati R. et al. Surgical approach to non-small cell lung cancer involving the chest wall. J Exp Clin Cancer Res. 2000 Mar;19(1):41-4. 122.Burkhart H M., Allen M S., Nichols F C. et al. Results of en bloc resection for bronchogenic carcinoma with chest wall invasion. J Thorac Cardiovasc Surg 2002;123:670-5 123.Roviaro G., Varoli F.; Grignani F. Non-small Cell Lung Cancer With Chest Wall Invasion Chest. 2003;123:1341-1347. 124.Matsuoka H, Nichio W., Okada M. et al. Resection of chest wall invasion in patients with non-small cell lung cancer.Eur J Cardiothorac Surg. 2004 Dec;26(6):1200-4. 125.Facciolo F., Cardillo G., Lopergolo M., et al. Chest wall invasion in non-small cell lung carcinoma: a rationale for en bloc resection. J. Thorac. Cardiovasc. Surg., 2001, 121:649-56. 126.Yokoi K, Tsuchiya R, Mori T, et al. Results of surgical treatment of lung cancer involving diaphragm. J Thorac Cardiovasc Surg 2000; 120: 799 - 805. 127.Pearson FG, DeLarue NC, Ilves R, et al: Significance of positive superior mediastinal nodes identified at mediastinoscopy in patients with resectable cancer of the lung. J Thorac Cardiovasc Surg 83:1, 1982 128.Tanaka F, Yanagihara K, Otake Y, Prognostic factors in resected pathologic (p-) stage IIIA-N2, non-small-cell lung cancer. Ann Surg Oncol. 2004 Jun;11(6):612-8. 129.Ohta Y., Shimixu Y., Minato H. et al. Results of initial operations in non-small cell lung cancer patients with single-level N2 disease. Ann Thorac Surg. 2006 Feb;81(2):427-33. 130.Suzuki K., Nagai K., Yoshida J. et al. The prognosis of surgically resected N2 non-small cell lung cancer: the importance of clinical N status.J Thorac Cardiovasc Surg. 1999 Jul;118(1):145-53. 131.Усков Д.А., Макеева И.В., Поме А.В. и др. Неоадьювантная химиотерапия немелкоклеточного рака легкого. Росс. Онкол. Журнал, 2001, N 3, с. 4-9. 132.Добродеев А.Ю. Комбинированное лечение рака легкого с интраоперационной лучевой терапией в условиях радиосенсибилизации цисплатином. Автореф. Дисс. На соиск., учен., степ., канд., мед., наук, Томск, 2004, 20 с. 133.Потанин А.В. Отдаленные результаты хирургического и комбинированного лечения больных немелкоклетьочным раком легкого. Автореф. Дисс. На соиск., учен., степ., канд., мед., наук, Казань, 2005, 24 с. 134.Maas K.W., van Swieten H.A., van Munnink V., Hofman P. et al. Combined modality treatment in stage IIIA/B non-small cell lung cancer. Citation: Lung Cancer 2003, Vol. 41, Supplement 2, Page 155. 135.De Leyn P., Decker G. Surgical treatment of non-small cell lung cancer. Rev Mal Respir, November 1, 2004; 21(5 Pt 1): 971-82. 136.Bradley J.D., Paulus R., Graham M.V., Ettinger D.S. et al. Phase II trial of postoperative adjuvant paclitaxel/carboplatin and thoracic radiotherapy in resected stage II and IIIA non-small cell lung cancer: promising long-term results of the Radiation Therapy Oncology Group - RTOG 9705. J.Clin Oncol., 2005, may 20;23(15):3480-7. 137.Machtay B M., Lee J. H., Shrager J.B., Kaiser L.R. et al. Risk of Death From Intercurrent Disease Is Not Excessively Increased by Modern Postoperative Radiotherapy for High-Risk Resected Non - Small-Cell Lung Carcinoma. Journal of Clinical Oncology, Vol 19, Issue 19 (October), 2001: 3912-3917 138.Stamatis G., Wilke H., Eberhardt W., Budach V. et al. Surgery of locally advanced non-small cell bronchial cancer after intensive preoperative chemo-/radiotherapy. Chirurg. 1994, Jan; 65(1):42-7. 139.Takamori S., Rikimaru T., Hayashi A., Tayama K, et al. A preoperative alternating chemotherapy and radiotherapy program for patients with stage IIIA (N2) non-small cell lung cancer. Cancer. 2000 Jul;29(1):49-56. 140.Hainsworth J.D., Gray J.R., Litchy S., Bearden J.D. et al. A phase II trial of preoperative concurrent radiation therapy and weekly paclitaxel/carboplatin for patients with locally advanced non-small-cell lung cancer. Clin Lung Cancer. 2004 Jul;6(1):33-42. 141.Friedel G., Hruska D., Budach W., Wolf M. et al. Neoadjuvant chemoradiotherapy of stage III non-small-cell lung cancer. Lung Cancer. 2000 Dec;30(3):175-85. 142.Hillejan L, Muller MR, Eberhardt W, Stuben G, Neoadjuvant chemotherapy and chemoradiotherapy in surgically treated non-small-cell stage III bronchial carcinoma. Kongressbd Dtsch Ges Chir Kongr. 2001;118:601-5. 143.Galetta D. Cesario A., Margaritora S., Porziella V. et al. Enduring challenge in the treatment of nonsmall cell lung cancer with clinical stage IIIB: results of a trimodality approach. Ann Thorac Surg 2003;76:1802-1809. 144.Marino P, Preatoni A, Cantoni A: Randomized trials of radiotherapy alone vs combined chemotherapy and radiotherapy in stages IIIA and IIIB non-small cell lung cancer. Cancer 76:593-601, 1995 145.Curran W, Scott C, Langer C, et al: Long-term benefit is observed in Phase III comparison of sequential vs concurrent chemo-radiation for patients with unresectable stage III NSCLC: RTOG 9410 (abstract 2499). Proc Am Soc Clin Oncol 22:621, 2003. 146.Noda K, Nishiwaki Y, Kawahara M, et al: Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small cell lung cancer. N Engl J Med 346:85-91, 2002. 147.Schild S, Brindle J, Geyer S, et al: Long-term results of a Phase III trial comparing once-daily radiotherapy with twice-daily radiotherapy in limited-stage small-cell lung cancer. Int J Radiat Oncol Biol Phys 59:943-951, 2004. 148.Жарков В.В. Моисеев П.И., Курчин В.П. Адьювантная полихимиотерапия и профилактическое облучение головного мозга в лечении оперированных больных мелкоклеточным раком легкого. В кн: Современные технологии в онкологии. Ростов на дону, 2005, том 1, с. 323-324 149.Зинченко С.В., Потанин В.П. Хирургическое лечение, как профилактика локорегионарных рецидивов при мелкоклеточном раке легкого. В кн: Современные технологии в онкологии. Ростов на дону, 2005, том 1, с.324-325. 150.Lewinski T, Zulawski M, Turski C, Pietraszek A. Small cell lung cancer I--III A: cytoreductive chemotherapy followed by resection with continuation of chemotherapy. Eur J Cardiothorac Surg. 2001 Aug;20(2):391-8. 151.Su X.D.,Huang Z.F., Rong T.H., Yang M.T. Combined surgical treatment for limited small cell lung cancer: clinical analysis of 51 cases. Ai Zheng. 2003 Oct;22(10):1099-101. 152.Nakamura H. Kato Y., Kato H. Outcome of surgery for small cell lung cancer -- response to induction chemotherapy predicts survival.Thorac Cardiovasc Surg. 2004 Aug;52(4):206-10. 153.Auperin A, Arriagada R, Pignon J, et al: Prophylactic cranial irradiation for patients with small cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group. N Engl J Med 341:476-484, 1999. 154.Бычков М.Б. Мелкоклеточные рак легкого. Эволюция химиотерапии за последние 20 лет. Материалы III съезда онкологов и радиологов СНГ, Минск, 2004, часть 1, 151-153. document: $pr: version: 01-2007.1 codepage: windows-1251 type: klinrek id: kli9995760 : 09.2. КАРЦИНОИДНЫЕ ОПУХОЛИ ЛЕГКИХ meta: author: fio[ru]: А.Х. Трахтенберг, К.И. Колбанов, В.В. Соколов, Л.В. Телегина codes: next: type: dklinrek code: III.IV type: dkli00023 Дата добавления: 2015-01-18 | Просмотры: 1279 | Нарушение авторских прав |